Research Article

Promoter Hypermethylation of the EMP3 Gene in a Series of 229 Human Gliomas

Table 2

Frequency of EMP3 promoter methylation in glioma types.

Tumor typePatients (n)EMP3 hypermethylation (%) P value

Astrocytic tumors 10018 (18%)
(WHO grades I–IV)
Oligodendroglial tumors 7346 (63%)<0.0001
(WHO grades II-III)
Oligoastrocytomas 2014 (70%)0.0001
(WHO grades II-III)