Research Article
Promoter Hypermethylation of the EMP3 Gene in a Series of 229 Human Gliomas
Table 5
Correlation between the methylation status of the EMP3 gene by MS-PCR and EMP3 protein expression by IHC.
| Tumor type | Total cases (n) | EMP3 methylation status | IHC protein expression | Positive | Negative |
| Astrocytic tumors | 26 | Methylated | 1 | 7 | Unmethylated | 15 | 3 | Oligodendroglial tumors | 57 | Methylated | 5 | 33 | Unmethylated | 13 | 6 | Oligoastrocytomas | 10 | Methylated | 3 | 5 | Unmethylated | 2 | 0 | GBMs | 9 | Methylated | 0 | 2 | Unmethylated | 7 | 0 |
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