Research Article

Promoter Hypermethylation of the EMP3 Gene in a Series of 229 Human Gliomas

Table 5

Correlation between the methylation status of the EMP3 gene by MS-PCR and EMP3 protein expression by IHC.

Tumor typeTotal cases (n)EMP3 methylation statusIHC protein expression
PositiveNegative

Astrocytic tumors 26Methylated17
Unmethylated153
Oligodendroglial tumors57Methylated533
Unmethylated136
Oligoastrocytomas10Methylated35
Unmethylated20
GBMs9Methylated02
Unmethylated70