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BioMed Research International
Volume 2013 (2013), Article ID 757459, 7 pages
http://dx.doi.org/10.1155/2013/757459
Clinical Study

2-Hour Postload Serum Glucose Levels and Maternal Blood Pressure as Independent Predictors of Birth Weight in “Appropriate for Gestational Age” Neonates in Healthy Nondiabetic Pregnancies

1Biochemistry Department, College of Medicine, Sultan Qaboos University, P.O. Box 35, 123, Muscat, Oman
2Obstetrics and Gynecology, College of Medicine, Sultan Qaboos University Hospital, P.O. Box 35, 123, Muscat, Oman
3College of Medicine, Sultan Qaboos University, P.O. Box 35, 123, Muscat, Oman

Received 30 April 2013; Revised 3 August 2013; Accepted 19 August 2013

Academic Editor: Winfried Randerath

Copyright © 2013 Jumana Saleh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. C. Han, D. A. Lawlor, and S. Y. Kimm, “Childhood obesity,” The Lancet, vol. 375, no. 9727, pp. 1737–1748, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. E. L. Ding and F. B. Hu, “Determining origins and causes of childhood obesity via mendelian randomization analysis,” PLoS Medicine, vol. 5, no. 3, article e65, 2008. View at Publisher · View at Google Scholar · View at Scopus
  3. D. Ludwig, “Childhood obesity—the shape of things to come,” The New England Journal of Medicine, vol. 357, no. 23, pp. 2325–2327, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. D. Ludwig and J. Currie, “The association between pregnancy weight gain and birthweight: a within-family comparison,” The Lancet, vol. 376, no. 9745, pp. 984–990, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. N. F. Krebs, M. S. Jacobson, and the American Academy of Pediatrics Committee on Nutrition, “Prevention of pediatric overweight and obesity,” Pediatrics, vol. 112, no. 2, pp. 424–430, 2003. View at Publisher · View at Google Scholar
  6. L. Ay, C. J. Kruithof, R. Bakker et al., “Maternal anthropometrics are associated with fetal size in different periods of pregnancy and at birth. The generation R study,” International Journal of Obstetrics and Gynaecology, vol. 116, no. 7, pp. 953–963, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. M. Maresh, “Screening for gestational diabetes mellitus,” Seminars in Fetal and Neonatal Medicine, vol. 10, no. 4, pp. 317–323, 2005. View at Publisher · View at Google Scholar · View at Scopus
  8. D. Sacks, “Big babies in pregnancies complicated by diabetes: is it all about maternal glucose?” Perinatology, vol. 1, no. 4, pp. 30–36, 2010.
  9. D. Churchill, I. J. Perry, and D. G. Beevers, “Ambulatory blood pressure in pregnancy and fetal growth,” The Lancet, vol. 349, no. 9044, pp. 7–10, 1997. View at Publisher · View at Google Scholar · View at Scopus
  10. H. Yadav and N. Lee, “Maternal factors in predicting low birth weight babies,” Medical Journal of Malaysia, vol. 68, no. 1, pp. 44–47, 2013.
  11. U. M. Schaefer-Graf, K. Graf, I. Kulbacka et al., “Maternal lipids as strong determinants of fetal environment and growth in pregnancies with gestational diabetes mellitus,” Diabetes Care, vol. 31, no. 9, pp. 1858–1863, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. K. K. Ong, B. Diderholm, G. Salzano et al., “Pregnancy insulin, glucose, and BMI contribute to birth outcomes in nondiabetic mothers,” Diabetes Care, vol. 31, no. 11, pp. 2193–2197, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. G. Farmer, G. Russell, D. R. Hamilton-Nicol et al., “The influence of maternal glucose metabolism on fetal growth, development and morbidity in 917 singleton pregnancies in nondiabetic women,” Diabetologia, vol. 31, no. 3, pp. 134–141, 1988. View at Scopus
  14. M. Bonomo, D. Corica, E. Mion et al., “Evaluating the therapeutic approach in pregnancies complicated by borderline glucose intolerance: a randomized clinical trial,” Diabetic Medicine, vol. 22, no. 11, pp. 1536–1541, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. D. M. Jensen, P. Damm, B. Sørensen et al., “Clinical impact of mild carbohydrate intolerance in pregnancy: a study of 2904 nondiabetic Danish women with risk factors for gestational diabetes mellitus,” American Journal of Obstetrics and Gynecology, vol. 185, no. 2, pp. 413–419, 2001. View at Publisher · View at Google Scholar · View at Scopus
  16. P. M. Catalano, A. Thomas, L. Huston-Presley, and S. B. Amini, “Increased fetal adiposity: a very sensitive marker of abnormal in utero development,” American Journal of Obstetrics and Gynecology, vol. 189, no. 6, pp. 1698–1704, 2003. View at Publisher · View at Google Scholar · View at Scopus
  17. A. Fraser, K. Tilling, C. MacDonald-Wallis et al., “Association of maternal weight gain in pregnancy with offspring obesity and metabolic and vascular traits in childhood,” Circulation, vol. 121, no. 23, pp. 2557–2564, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. S. Upadhyay, R. P. Biccha, M. T. Sherpa, S. Shrestha, and P. P. Panta, “Association between maternal body mass index and the birth weight of neonates,” Nepal Medical College Journal, vol. 13, no. 1, pp. 42–45, 2011. View at Scopus
  19. S. S. Merchant, I. A. Momin, A. A. Sewani, and N. F. Zuberi, “Effect of prepregnancy body mass index and gestational weight gain on birth weight,” The Journal of the Pakistan Medical Association, vol. 49, no. 1, pp. 23–25, 1999. View at Scopus
  20. C. A. Asplund, D. A. Seehusen, T. L. Callahan, and C. Olsen, “Percentage change in antenatal body mass index as a predictor of neonatal macrosomia,” Annals of Family Medicine, vol. 6, no. 6, pp. 550–554, 2008. View at Publisher · View at Google Scholar · View at Scopus
  21. S. T. Blackburn and D. L. Loper, “Carbohydrate, fat, and protein metabolism,” in Maternal, Fetal and Neonatal Physiology: A Clinical Perspective, T. Eoyang, Ed., pp. 583–613, W. B. Saunders, Philadelphia, Pa, USA, 1992.
  22. L. Sekhavat, F. Zare, and S. Akhavan Karbasi, “Maternal serum triglyceride at midpregnancy and newborn weight in nondiabetic and normal BMI women,” Nepal Journal of Obstetrics and Gynaecology, vol. 3, no. 1, pp. 19–23, 2008.
  23. J. Saleh, H. Al-Riyami, T. Chaudhary, and K. Cianflone, “Cord blood ASP is predicted by maternal lipids and correlates with fetal birth weight,” Obesity, vol. 16, no. 6, pp. 1193–1198, 2008. View at Publisher · View at Google Scholar · View at Scopus
  24. G. Di Cianni, R. Miccoli, L. Volpe et al., “Maternal triglyceride levels and newborn weight in pregnant women with normal glucose tolerance,” Diabetic Medicine, vol. 22, no. 1, pp. 21–25, 2005. View at Publisher · View at Google Scholar · View at Scopus
  25. R. H. Knopp, B. Bonet, and X. Zhu, “Lipid metabolism in pregnancy,” in Principles of Perinatal-Neonatal Metabolism, R. M. Cowett, Ed., pp. 221–258, Springer, New York, NY, USA, 2nd edition, 1988.
  26. M. Kitajima, S. Oka, I. Yasuhi, M. Fukuda, Y. Rii, and T. Ishimaru, “Maternal serum triglyceride at 24–32 weeks' gestation and newborn weight in nondiabetic women with positive diabetic screens,” Obstetrics and Gynecology, vol. 97, no. 5, pp. 776–780, 2001. View at Scopus
  27. T. L. Hernandez, J. E. Friedman, R. E. Van Pelt, and L. A. Barbour, “Patterns of glycemia in normal pregnancy: should the current therapeutic targets be challenged?” Diabetes Care, vol. 34, no. 7, pp. 1660–1668, 2011. View at Scopus
  28. B. E. Metzger, L. P. Lowe, A. R. Dyer, et al., “HAPO study cooperative research group hyperglycemia and adverse pregnancy outcomes,” The New England Journal of Medicine, vol. 358, pp. 1991–2002, 2008. View at Publisher · View at Google Scholar
  29. Z. Kerényi, G. Tamás, M. Kivimäki et al., “Maternal glycemia and risk of large-for-gestational-age babies in a population-based screening,” Diabetes Care, vol. 32, no. 12, pp. 2200–2205, 2009. View at Publisher · View at Google Scholar
  30. M. C. Breschi, G. Seghieri, G. Bartolomei, A. Gironi, S. Baldi, and E. Ferrannini, “Relation of birthweight to maternal plasma glucose and insulin concentrations during normal pregnancy,” Diabetologia, vol. 36, no. 12, pp. 1315–1321, 1993. View at Publisher · View at Google Scholar · View at Scopus
  31. L. Jovanovic-Peterson, C. M. Peterson, G. F. Reed et al., “Maternal postprandial glucose levels and infant birth weight: the diabetes in early pregnancy study,” American Journal of Obstetrics and Gynecology, vol. 164, no. 1, part 1, pp. 103–111, 1991. View at Scopus
  32. G. Mello, E. Parretti, R. Cioni et al., “The 75-gram glucose load in pregnancy: relation between glucose levels and anthropometric characteristics of infants born to women with normal glucose metabolism,” Diabetes Care, vol. 26, no. 4, pp. 1206–1210, 2003. View at Publisher · View at Google Scholar · View at Scopus
  33. World Health Organization, Definition and Diagnosis of Diabetes Mellitus and Intermediate Hyperglycemia: Report of a WHO/IDF Consultation, World Health Organization, Geneva, Switzerland, 2006.
  34. N. S. The, L. S. Adair, and P. Gordon-Larsen, “A study of the birth weight-obesity relation using a longitudinal cohort and sibling and twin pairs,” American Journal of Epidemiology, vol. 172, no. 5, pp. 549–557, 2010. View at Publisher · View at Google Scholar · View at Scopus
  35. 2013, http://www.webmd.com/baby/guide/healthy-weight-gain.
  36. M. Sermer, C. D. Naylor, D. J. Gare et al., “Impact of increasing carbohydrate intolerance on maternal-fetal outcomes in 3637 women without gestational diabetes,” American Journal of Obstetrics and Gynecology, vol. 173, no. 1, pp. 146–156, 1995. View at Scopus
  37. D. A. Sacks, J. S. Greenspoon, S. Abu-Fadil, H. M. Henry, G. Wolde-Tsadik, and J. F. Yao, “Toward universal criteria for gestational diabetes: the 75-gram glucose tolerance test in pregnancy,” American Journal of Obstetrics and Gynecology, vol. 172, pp. 607–614, 1995. View at Publisher · View at Google Scholar · View at Scopus
  38. L. Tallarigo, O. Giampietro, and G. Penno, “Relation of glucose tolerance to complications of pregnancy in nondiabetic women,” The New England Journal of Medicine, vol. 315, no. 16, pp. 989–992, 1986. View at Scopus
  39. R. R. Little, E. M. McKenzie, J. M. Shyken et al., “Lack of relationship between glucose tolerance and complications of pregnancy in nondiabetic women,” Diabetes Care, vol. 13, no. 5, pp. 483–487, 1990. View at Scopus
  40. J. Langhoff-Roos, L. Wibell, M. Gebre-Medhin, and G. Lindmark, “Placental hormones and maternal glucose metabolism: a study of fetal growth in normal pregnancy,” British Journal of Obstetrics and Gynaecology, vol. 96, no. 3, pp. 320–326, 1989. View at Scopus
  41. M. C. Breschi, G. Seghieri, G. Bartolomei, A. Gironi, S. Baldi, and E. Ferrannini, “Relation of birthweight to maternal plasma glucose and insulin concentrations during normal pregnancy,” Diabetologia, vol. 36, no. 12, pp. 1315–1321, 1993. View at Publisher · View at Google Scholar · View at Scopus
  42. J. C. Y. Louie, J. C. Brand-Miller, T. P. Markovic, G. P. Ross, and R. G. Moses, “Glycemic index and pregnancy: a systematic literature review,” Journal of Nutrition and Metabolism, vol. 2010, Article ID 282464, 8 pages, 2010. View at Publisher · View at Google Scholar
  43. J. Pedersen, “Weight and length at birth of infants of diabetic mothers,” Acta Endocrinologica, vol. 16, no. 4, pp. 330–342, 1954. View at Scopus
  44. O. Langer, “Fetal macrosomia: etiologic factors,” Clinical Obstetrics and Gynecology, vol. 43, no. 2, pp. 283–297, 2000. View at Publisher · View at Google Scholar · View at Scopus
  45. S. Lager and T. L. Powell, “Regulation of nutrient transport across the placenta,” Journal of Pregnancy, vol. 2012, Article ID 179827, 14 pages, 2012. View at Publisher · View at Google Scholar
  46. C. J. Nolan, S. F. Riley, M. T. Sheedy, J. E. Walstab, and N. A. Bescher, “Maternal serum triglyceride, glucose tolerance, and neonatal birth weight ratio in pregnancy,” Diabetes Care, vol. 18, no. 12, pp. 1550–1556, 1995. View at Scopus
  47. J. H. Grundt, J. Nakling, G. E. Eide, and T. Markestad, “Possible relation between maternal consumption of added sugar and sugar-sweetened beverages and birth weight–time trends in a population,” BMC Public Health, vol. 12, p. 901, 2012. View at Publisher · View at Google Scholar
  48. L. B. Nucci, B. B. Duncan, S. S. Mengue, L. Branchtein, M. I. Schmidt, and E. T. Fleck, “Assessment of weight gain during pregnancy in general prenatal care services in Brazil,” Cadernos de Saude Publica, vol. 17, no. 6, pp. 1367–1374, 2001. View at Scopus
  49. S. Kayemba-Kay's, C. Peters, M. P. Geary, N. R. Hill, D. R. Mathews, and P. C. Hindmarsh, “Maternal hyperinsulinism and glycaemic status in the first trimester of pregnancy are associated with the development of pregnancy-induced hypertension and gestational diabetes,” European Journal of Endocrinology, vol. 168, no. 3, pp. 413–418, 2013. View at Publisher · View at Google Scholar
  50. B. Khulan and A. J. Drake, “Glucocorticoids as mediators of developmental programming effects,” Clinical Endocrinology and Metabolism, vol. 26, no. 5, pp. 689–700, 2012. View at Publisher · View at Google Scholar
  51. American Heart Association, Understanding Blood Pressure Readings, American Heart Association, 2011.
  52. P. Painter, J. Cope, and J. Smith, “Reference information for the clinical laboratory,” in Tietz Text Book of Clinical Chemistry, C. Burtis and E. Ashwood, Eds., p. 1799, W. B. Saunders, Philadelphia, Pa, USA, 3rd edition, 1999.