Research Article
Chromosome Instability and Oxidative Stress Markers in Patients with Ataxia Telangiectasia and Their Parents
Table 1
Frequency of chromosomal breaks observed in the different groups and treatments.
| Frequency of chromosomal breaks | | Spontaneous | Bleomycin (6 μg/mL) | Radiation (3 Gy) |
| Patients | | | | Frequency (min × max) | 0.00–1.30 | 0.43–5.65 | 0.47–7.32 | frequencies/cell | 0.18 | 1.63 | 2.10 | cells (min × max) | 30 × 50 | 30 × 50 | 30 × 50 | Parents | | | | Frequency (min × max) | 0.00–0.13 | 0.00–1.27 | 0.23–0.93 | frequencies/cell | 0.02 | 0.56 | 0.52 | cells (min × max) | 30 × 50 | 5 × 50 | 21 × 50 | Control group | | | | Frequency (min × max) | 0.00–0.03 | 0.00–0.90 | 0.10–0.93 | frequencies/cell | 0.01 | 0.47 | 0.56 | cells (min × max) | 30 | 4 × 30 | 13 × 30 |
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: average frequency of chromosomal breaks per cell.
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