Chromosome Instability and Oxidative Stress Markers in Patients with Ataxia Telangiectasia and Their Parents

Table 3

Statistical analysis comparing the chromosomal aberrations (CAs) between the different groups within each treatment.

Treatments	Chromosomal aberrations	𝑃 value of the Kruskal-Wallis test
Spontaneous	Chromatid breaks (chtb)	0.910
Bleomycin (6 μg/mL)		0.007*
Radiation (3 Gy)		0.000*
Spontaneous	Chromosome breaks (chrb)	0.289
Bleomycin (6 μg/mL)		0.036*
Radiation (3 Gy)		0.197
Spontaneous	Chromosome fragments	0.022*
Bleomycin (6 μg/mL)		0.009*
Radiation (3 Gy)		0.270
Spontaneous	Translocations (t)	0.097
Bleomycin (6 μg/mL)		0.100
Radiation (3 Gy)		0.004*
Spontaneous	Deletions (del)	0.002*
Bleomycin (6 μg/mL)		0.073
Radiation (3 Gy)		0.004*
Spontaneous	Interstitial deletions	1.000
Bleomycin (6 μg/mL)		0.293
Radiation (3 Gy)		1.000
Spontaneous	Dicentric chromosomes	1.000
Bleomycin (6 μg/mL)		0.439
Radiation (3 Gy)		1.000
Spontaneous	Triradial figures	1.000
Bleomycin (6 μg/mL)		0.005*
Radiation (3 Gy)		0.001*
Spontaneous	Quadriradial figures	1.000
Bleomycin (6 μg/mL)		0.228
Radiation (3 Gy)		0.222
Spontaneous	Ring chromosomes (r)	1.000
Bleomycin (6 μg/mL)		0.587
Radiation (3 Gy)		0.943
Spontaneous	Additional materials (add)	1.000
Bleomycin (6 μg/mL)		1.000
Radiation (3 Gy)		0.287
Spontaneous	Isochromosomes (iso)	1.00
Bleomycin (6 μg/mL)		0.293
Radiation (3 Gy)		1.00
Spontaneous	Chromatid failures (chtg)	0.027*
Bleomycin (6 μg/mL)		0.461
Radiation (3 Gy)		0.014*
Spontaneous	Chromosomal failures (chrg)	0.557
Bleomycin (6 μg/mL)		0.021*
Radiation (3 Gy)		0.461
Spontaneous	Fragile sites	0.591
Bleomycin (6 μg/mL)		0.314
Radiation (3 Gy)		0.004*

∗demonstrates the chromosomal aberrations with statistically significant differences.