Research Article

Genotoxicity of Polycyclic Aromatic Hydrocarbons and Nitro-Derived in Respirable Airborne Particulate Matter Collected from Urban Areas of Rio de Janeiro (Brazil)

Table 2

Induced mutagenic by airborne particulate matter organic extracts (rev/m3).

SiteMonthTA98YG1021YG1024
−S9+S9−S9+S9−S9+S9

Augustn.d.a15.80 ± 1.4013.90 ± 0.809.50 ± 1.4038.20 ± 1.6015.50 ± 1.40
1Septembern.d.a13.00 ± 2.106.10 ± 1.30n.d.a15.80 ± 2.503.40 ± 0.80
Octobern.d.an.d.a10.20 ± 1.306.40 ± 1.102.90 ± 0.60n.d.a

August17.00 ± 1.901.50 ± 0.5017.30 ± 1.805.70 ± 1.6043.40 ± 8.5010.70 ± 1.80
2September5.70 ± 0.90n.d.a13.90 ± 1.306.40 ± 1.2411.70 ± 2.506.00 ± 0.70
Octobern.d.an.d.a4.90 ± 0.70n.d.a3.80 ± 0.30n.d.a

August39.60 ± 11.9013.00 ± 2.304.40 ± 1.903.10 ± 0.8028.30 ± 3.102.30 ± 0.80
3September56.40 ± 20.6058.70 ± 11.8063.00 ± 3.2026.60 ± 3.9057.00 ± 6.9049.30 ± 3.90
October9.30 ± 1.8046.50 ± 4.2035.40 ± 0.8018.30 ± 1.8022.80 ± 2.006.00 ± 2.00

1: UERJ; 2: Avenida Brasil; 3: Rebouças tunnel. n.d.a: not detected. Negative control: DMSO for the mutagenicity assay without S9 mix was TA98, (28 ± 5); YG1021, (20 ± 2); YG1024, (18 ± 4). DMSO for the mutagenicity assay with S9 mix was TA98, (43 ± 3); YG1021, (35 ± 23); YG1024, (18 ± 5). Positive controls for the mutagenicity assay without S9 mix were 4-nitroquinoline oxide (0.5 µg/plate) for TA98, (853 ± 72); YG1021, (719 ± 75); YG1024, (1021 ± 54). Positive controls for the mutagenicity assay with S9 mix were 2-aminofluorene (1 µg/plate) for TA98, (214 ± 42); YG1021, (150 ± 32); YG1024, (219 ± 81).