Genotoxicity of Polycyclic Aromatic Hydrocarbons and Nitro-Derived in Respirable Airborne Particulate Matter Collected from Urban Areas of Rio de Janeiro (Brazil)
Table 4
Mitotic index and percentage of mitosis stages and mitotic aberrations in the root tip cells of A. cepa treated with organic extract derived at site 2.
Month
µg/mL
Mitotic index
% P.
% M.
% A.
% T.
% T.A.
% MCN
% Bridge
% Break
% Lagging
NC
0.08 ± 0.03
4.50
1.90
0.40
1.10
0.30
0.18
0.07
0.00
0.05
5
0.07 ± 0.03
3.20
1.60
0.90*
1.80
0.57
0.25
0.17
0.00
0.15
August
10
0.04 ± 0.01*
1.80*
0.80
0.40
0.60
0.41
0.03
0.06
0.16
0.16
15
0.04 ± 0.01*
0.33*
3.26
0.56
0.36
0.75*
0.03
0.23*
0.26*
0.23
20
0.04 ± 0.02*
2.53
1.23
0.46
0.76
0.19
0.00
0.00
0.16
0.03
25
0.04 ± 0.01*
0.10*
1.40
0.90*
1.40
0.70
0.00
0.50*
0.10
0.10
NC
0.02 ± 0.01
0.80
0.60
0.20
0.50
0.15
0.00
0.05
0.05
0.05
5
0.04 ± 0.02
1.10
1.30
0.80
0.50
0.54
0.04
0.20
0.08
0.22
September
10
0.07 ± 0.03
2.00
2.50*
1.50*
1.50
1.30*
0.10
0.40
0.40
0.40
15
0.01 ± 0.01
0.50
0.30
0.30
0.01*
0.60
0.40
0.05
0.05
0.10
20
0.06 ± 0.05
2.00
2.00
1.00
1.40
1.08*
0.06
0.33
0.26
0.43
25
0.01 ± 0.01
0.50
0.50
0.10
0.30
0.28
0.03
0.06
0.16
0.03
NC
0.05 ± 0.02
3.90
0.50
0.20
0.30
0.30
0.10
0.00
0.10
0.10
5
0.05 ± 0.01
2.00
1.50
0.70
1.30
0.67
0.00
0.17*
0.30
0.20
October
10
0.07 ± 0.01
1.70
1.80
0.80
3.20*
1.05
0.00
0.10
0.75
0.20
15
0.00 ± 0.00
0.00
0.00
0.00
0.00
0.00
0.00
0.00
0.00
0.00
20
0.00 ± 0.00
0.00
0.00
0.00
0.00
0.03
0.00
0.03
0.00
0.00
25
0.00 ± 0.00
0.00
0.00
0.00
0.00
0.00
0.00
0.00
0.00
0.00
P.: prophase; M.: metaphase; A.: anaphase; T.: telophase; T.A.: total abnormalities; MCN.: micronucleus; NC.: negative control—DMSO; positive control = benzo(a)pyrene 10 µg/mL (mitotic index = 0.00*; % T.A. = 0.20; % bridge = 0.10; % break =0.10) * ≤ 0.05.