Moscatilin Inhibits Lung Cancer Cell Motility and Invasion via Suppression of Endogenous Reactive Oxygen Species
Figure 2
Cytotoxicity of moscatilin on human lung H23 cells. (a) Cells were treated with various concentrations of moscatilin (0–5 μM) for 24 h. (b) Cells were treated with moscatilin (0-1 μM) for various times (0–72 h). Cytotoxicity was determined by 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. (c) After indicated treatment for 24 h, mode of cell death was examined by Hoechst33342/PI costaining assay and Annexin-V staining assay. (d) Cellular apoptosis was determined by DNA content analysis using flow cytometry. Data represent the means ± SD (). versus nontreated control cells.
