Supplementation with Natural Forms of Vitamin E Augments Antigen-Specific TH1-Type Immune Response to Tetanus Toxoid
Figure 3
The mice in the various groups were fed with Soya oil (vehicle), alpha-tocopherol (alpha-T), delta-tocotrienol (delta-T3), or tocotrienol-rich fraction (TRF). Mice in all groups were immunised intramuscularly with 4 Lf/mL of TT on days 14, 28, and 42. Serum was collected on day 0 (PB), day 28 (V1) and day 56 (V2). Serum levels of anti-TT were determined by ELISA. The values are presented as mean ± standard deviation (S.D.). The δ-T3 supplemented mice produced the highest anti-TT titres following booster vaccination. [*significant difference from vehicle-fed group; #significant difference from α-T supplemented group].
