Biochemical Characterization, Action on Macrophages, and Superoxide Anion Production of Four Basic Phospholipases A₂ from Panamanian Bothrops asper Snake Venom

Table 1

Toxic activities induced by B. asper snake venom from Panama.

Effect^a	Activity
Lethal (LD50; μg/mouse)	55
Edema-inducing (DEM; μg)^ab	1 ± 0.1
Hemorrhagic (MHD, μg)^ab	1.2 ± 0.2
Coagulant (MCD; μg)^ab	3.5 ± 0.05
Fibrinolytic (MFD; μg)	0.5
Indirect hemolitic (MHeD; μg)^ab	7.2 ± 0.01
Phospholipase A2 (mEq/mg·min)^ab	27.2 ± 0.45
Myotoxic (MMD, μg)^ab	10 ± 1

^aResults are presented as mean ± SD. Except for lethality and fibrinolytic activity.
^bAll experiments were carried out in triplicate.