Chitosan Dermal Substitute and Chitosan Skin Substitute Contribute to Accelerated Full-Thickness Wound Healing in Irradiated Rats

Figure 6

Expression of K10 along the migratory tongue. On day 7 postwound, there is no expressions in the irradiated rat ((b), (c)). However, the wound with chitosan skin substitute slightly expressed K10 (a with asterisk), and the nonirradiated rat showed similar results ((d), (e), (f)). K10 started to be slightly expressed in the irradiated rat on day 14 ((g), (h), (i)). K10 was highly expressed on day 14 in the nonirradiated rat ((j), (k), (l)) and on day 21 in the irradiated rat ((m), (n), (o)). The nonirradiated rats continuously expressed K10 on day 21 ((p), (q), (r)). Scale bar: 20 µm. (E: epidermis, D: dermis).

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