The use of Multidimensional Data to Identify the Molecular Biomarker for Pancreatic Ductal Adenocarcinoma

Table 1

Significant TF, miRNA, and KEGG pathway that are enriched with survival genes.

Transcription factor gene sets	FDR	References
TP53	0.0141	[14, 15]
CEBPA	0.0187	Novel
STAT6	0.0194	Novel
PGR	0.0225	Novel
E2F1	0.0329	[16, 17]
MicroRNA gene sets
hsa-miR-543	0.0001	Novel
hsa-miR-576	0.0004	[18]
hsa-miR-32	0.0008	Novel
hsa-miR-545	0.0021	Novel
hsa-miR-608	0.0072	[19]
KEGG pathways
Glycolysis/gluconeogenesis	0.0001	[33, 34]
Circadian rhythm	0.0001	[20, 21]
Phosphatidylinositol signaling system	0.0001	[29, 30]
Hedgehog signaling pathway	0.0007	[31, 32]
Insulin signaling pathway	0.0007	[35, 36]