Predicting the DPP-IV Inhibitory Activity <svg     style="vertical-align:-5.1138pt;width:50.737499px;" id="M1" height="21.4" version="1.1" viewBox="0 0 50.737499 21.4" width="50.737499"  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg">
	
		
			<g transform="matrix(.022,-0,0,-.022,.062,14.975)"><path id="x70" d="M169 380l92 53q26 16 49 16q80 0 128.5 -56t48.5 -133q0 -108 -72.5 -180.5t-176.5 -91.5q-38 1 -69 18v-131q0 -57 13 -70t71 -18v-27h-236v27q49 5 61 17t12 61v452q0 48 -9.5 58.5t-56.5 16.5v24q66 11 145 43v-79zM169 346v-270q37 -39 94 -39q63 0 101.5 50
t38.5 134q0 78 -38.5 123t-95.5 45q-45 0 -100 -43z" /></g><g transform="matrix(.022,-0,0,-.022,11.809,14.975)"><path id="x49" d="M303 0h-265v28q62 5 76 19.5t14 77.5v400q0 63 -14 77.5t-76 19.5v28h265v-28q-62 -5 -76 -19.5t-14 -77.5v-400q0 -64 14 -78t76 -19v-28z" /></g><g transform="matrix(.022,-0,0,-.022,19.453,14.975)"><path id="x43" d="M614 175l29 -10q-33 -109 -57 -154q-121 -26 -184 -26q-90 0 -160.5 29t-112.5 77t-63.5 105.5t-21.5 119.5q0 157 108 253t277 96q36 0 71.5 -5t69 -13.5t36.5 -8.5q15 -102 20 -150l-29 -8q-20 79 -66.5 114t-128.5 35q-119 0 -187.5 -86t-68.5 -207
q0 -140 73.5 -227.5t188.5 -87.5q73 0 119.5 37.5t86.5 116.5z" /></g>

			<g transform="matrix(.016,-0,0,-.016,34.363,21.137)"><path id="x1D7D3" d="M148 676h322l-45 -127h-276l-22 -81q103 -6 151 -20q82 -23 127.5 -79.5t45.5 -134.5q0 -109 -79 -176q-78 -66 -203 -66q-64 0 -105.5 25.5t-41.5 62.5q0 26 17.5 43.5t43.5 17.5q47 0 100 -46q49 -42 90 -42q42 0 71 29.5t29 74.5q0 51 -36.5 90.5t-105.5 61.5
q-47 14 -180 22z" /></g><g transform="matrix(.016,-0,0,-.016,42.208,21.137)"><path id="x1D7CE" d="M476 337q0 -157 -63 -254q-63 -96 -162 -96t-163 96q-64 95 -64 251q0 51 7 99.5t24.5 95.5t43 81.5t65.5 56t89 21.5q75 0 127 -55q96 -97 96 -296zM318 224v225q0 111 -16 161t-53 50t-52 -48.5t-15 -162.5v-225q0 -112 16 -160.5t53 -48.5t52 47.5t15 161.5z" /></g>

		
	
</svg> Based on Their Physicochemical Properties

<table>Predicted versus experimental pIC<sub>50</sub> for the training (circles for fitting and triangle for CV, respectively) and test (stars) sets.</table>

BioMed Research International

fig3

Figure 3

Figure 3: Predicting the DPP-IV Inhibitory Activity <svg     style="vertical-align:-5.1138pt;width:50.737499px;" id="M1" height="21.4" version="1.1" viewBox="0 0 50.737499 21.4" width="50.737499"  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg">
	
		
			<g transform="matrix(.022,-0,0,-.022,.062,14.975)"><path id="x70" d="M169 380l92 53q26 16 49 16q80 0 128.5 -56t48.5 -133q0 -108 -72.5 -180.5t-176.5 -91.5q-38 1 -69 18v-131q0 -57 13 -70t71 -18v-27h-236v27q49 5 61 17t12 61v452q0 48 -9.5 58.5t-56.5 16.5v24q66 11 145 43v-79zM169 346v-270q37 -39 94 -39q63 0 101.5 50
t38.5 134q0 78 -38.5 123t-95.5 45q-45 0 -100 -43z" /></g><g transform="matrix(.022,-0,0,-.022,11.809,14.975)"><path id="x49" d="M303 0h-265v28q62 5 76 19.5t14 77.5v400q0 63 -14 77.5t-76 19.5v28h265v-28q-62 -5 -76 -19.5t-14 -77.5v-400q0 -64 14 -78t76 -19v-28z" /></g><g transform="matrix(.022,-0,0,-.022,19.453,14.975)"><path id="x43" d="M614 175l29 -10q-33 -109 -57 -154q-121 -26 -184 -26q-90 0 -160.5 29t-112.5 77t-63.5 105.5t-21.5 119.5q0 157 108 253t277 96q36 0 71.5 -5t69 -13.5t36.5 -8.5q15 -102 20 -150l-29 -8q-20 79 -66.5 114t-128.5 35q-119 0 -187.5 -86t-68.5 -207
q0 -140 73.5 -227.5t188.5 -87.5q73 0 119.5 37.5t86.5 116.5z" /></g>

			<g transform="matrix(.016,-0,0,-.016,34.363,21.137)"><path id="x1D7D3" d="M148 676h322l-45 -127h-276l-22 -81q103 -6 151 -20q82 -23 127.5 -79.5t45.5 -134.5q0 -109 -79 -176q-78 -66 -203 -66q-64 0 -105.5 25.5t-41.5 62.5q0 26 17.5 43.5t43.5 17.5q47 0 100 -46q49 -42 90 -42q42 0 71 29.5t29 74.5q0 51 -36.5 90.5t-105.5 61.5
q-47 14 -180 22z" /></g><g transform="matrix(.016,-0,0,-.016,42.208,21.137)"><path id="x1D7CE" d="M476 337q0 -157 -63 -254q-63 -96 -162 -96t-163 96q-64 95 -64 251q0 51 7 99.5t24.5 95.5t43 81.5t65.5 56t89 21.5q75 0 127 -55q96 -97 96 -296zM318 224v225q0 111 -16 161t-53 50t-52 -48.5t-15 -162.5v-225q0 -112 16 -160.5t53 -48.5t52 47.5t15 161.5z" /></g>

		
	
</svg> Based on Their Physicochemical Properties 

BioMed Research International

Predicting the DPP-IV Inhibitory Activity Based on Their Physicochemical Properties

Figure 3