Research Article
Optimization Studies on Compression Coated Floating-Pulsatile Drug Delivery of Bisoprolol
Table 2
Preparation of the Floating Pulsatile Release Tablet (FPRT) trial batches individual polymer.
| Sr. no. | Ingredients | Formulation codes | P1 | P2 | P3 | P4 | P5 | P6 |
| 1 | Polyox-205 | 160 | 140 | 120 | — | — | — | 2 | Polyox-N12K | — | — | — | 150 | 130 | 110 | 3 | NaHCO3 | 45 | 45 | 45 | 45 | 45 | 45 | 4 | Citric acid | 15 | 15 | 15 | 15 | 15 | 15 | 5 | Ca2PO4 | — | 20 | 40 | 10 | 30 | 50 |
|
|