Knockout of Density-Enhanced Phosphatase-1 Impairs Cerebrovascular Reserve Capacity in an Arteriogenesis Model in Mice

Figure 1

(a) Control mice (𝑛=5) and mice after CCAO (𝑛=5) were subjected to latex perfusion for visualization of the collateral vessel network. Red arrows indicate the ipsilateral ACA. (b) Quantification of the external vessel diameters (*𝑃<0.05 versus control mice). (c) Gene expression analyses of the PDGF-βR, VEGFR2, PDGF- and VEGF-ligands, and receptor-targeting PTPs in the ACA (𝑛=4). PCA: posterior cerebral artery, PComA: posterior communicating artery, MCA: middle cerebral artery, and ACA: anterior cerebral artery.

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