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BioMed Research International
Volume 2013 (2013), Article ID 802149, 9 pages
Knockout of Density-Enhanced Phosphatase-1 Impairs Cerebrovascular Reserve Capacity in an Arteriogenesis Model in Mice
1Center for Cardiovascular Research (CCR), Institute of Laboratory Medicine, Clinical Chemistry and Pathobiochemistry,
Charité-University Medicine Berlin, Hessische Straße 3-4, 10115 Berlin, Germany
2Department of Internal Medicine, Cardiology and Angiology, Richard Thoma Laboratories for Arteriogenesis, Center for Cardiovascular Research, Charité-University Medicine Berlin, Hessische Straße 3-4, 10115 Berlin, Germany
3Department of Cardiology, Charité-University Medicine Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
4Clinic for Radiology and Nuclear Medicine, Charité-University Medicine Berlin, Center for Muscle and Bone Research, Free University Berlin, Hindenburgdamm 30, 12203 Berlin, Germany
5Center for Cardiovascular Research (CCR), and Department of Experimental Medicine, Charité-University Medicine Berlin, Hessische Straße 3-4, 10115 Berlin, Germany
6Institute of Molecular Cell Biology, Center for Molecular Biomedicine, Jena University Hospital, Hans-Knöll-Straße 3-4, 07745 Jena, Germany
Received 25 April 2013; Revised 27 June 2013; Accepted 17 July 2013
Academic Editor: Goutam Ghosh Choudhury
Copyright © 2013 Daniel Hackbusch et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- A. Alonso, J. Sasin, N. Bottini et al., “Protein tyrosine phosphatases in the human genome,” Cell, vol. 117, no. 6, pp. 699–711, 2004.
- L. G. Borges, R. A. Seifert, F. J. Grant et al., “Cloning and characterization of rat density-enhanced phosphatase-1, a protein tyrosine phosphatase expressed by vascular cells,” Circulation Research, vol. 79, no. 3, pp. 570–580, 1996.
- M. A. de la Fuente-García, J. M. Nicolás, J. H. Freed et al., “CD148 is a membrane protein tyrosine phosphatase present in all hematopoietic lineages and is involved in signal transduction on lymphocytes,” Blood, vol. 91, no. 8, pp. 2800–2809, 1998.
- A. Östman, Q. Yang, and N. K. Tonks, “Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density,” Proceedings of the National Academy of Sciences of the United States of America, vol. 91, no. 21, pp. 9680–9684, 1994.
- M. M. Keane, G. A. Lowrey, S. A. Ettenberg, M. A. Dayton, and S. Lipkowitz, “The protein tyrosine phosphatase DEP-1 is induced during differentiation and inhibits growth of breast cancer cells,” Cancer Research, vol. 56, no. 18, pp. 4236–4243, 1996.
- A. Petermann, D. Haase, A. Wetzel et al., “Loss of the protein-tyrosine phosphatase DEP-1/PTPRJ drives meningioma cell motility,” Brain Pathology, vol. 21, no. 4, pp. 405–418, 2011.
- C. Aya-Bonilla, M. R. Green, E. Camilleri et al., “High-resolution loss of heterozygosity screening implicates PTPRJ as a potential tumor suppressor gene that affects susceptibility to Non-Hodgkin's Lymphoma,” Genes Chromosomes Cancer, vol. 52, no. 5, pp. 467–479, 2013.
- P. Hillmeister, K. E. Lehmann, A. Bondke et al., “Induction of cerebral arteriogenesis leads to early-phase expression of protease inhibitors in growing collaterals of the brain,” Journal of Cerebral Blood Flow and Metabolism, vol. 28, no. 11, pp. 1811–1823, 2008.
- M. Heil, M. Clauss, K. Suzuki et al., “Vascular endothelial growth factor (VEGF) stimulates monocyte migration through endothelial monolayers via increased integrin expression,” European Journal of Cell Biology, vol. 79, no. 11, pp. 850–857, 2000.
- S. Wu, X. Wu, W. Zhu, W. Cai, J. Schaper, and W. Schaper, “Immunohistochemical study of the growth factors, aFGF, bFGF, PDGF-AB, VEGF-A and its receptor (Flk-1) during arteriogenesis,” Molecular and Cellular Biochemistry, vol. 343, no. 1-2, pp. 223–229, 2010.
- D. W. Leung, G. Cachianes, W. J. Kuang, D. V. Goeddel, and N. Ferrara, “Vascular endothelial growth factor is a secreted angiogenic mitogen,” Science, vol. 246, no. 4935, pp. 1306–1309, 1989.
- P. G. Lloyd, B. M. Prior, H. Li, H. T. Yang, and R. L. Terjung, “VEGF receptor antagonism blocks arteriogenesis, but only partially inhibits angiogenesis, in skeletal muscle of exercise-trained rats,” The American Journal of Physiology—Heart and Circulatory Physiology, vol. 288, no. 2, pp. H759–H768, 2005.
- E. Toyota, D. C. Warltier, T. Brock et al., “Vascular endothelial growth factor is required for coronary collateral growth in the rat,” Circulation, vol. 112, no. 14, pp. 2108–2113, 2005.
- M. R. Kano, Y. Morishita, C. Iwata et al., “VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B-PDGFRβ signaling,” Journal of Cell Science, vol. 118, no. 16, pp. 3759–3768, 2005.
- K. Kappert, J. Paulsson, J. Sparwel et al., “Dynamic changes in the expression of DEP-1 and other PDGF receptor-antagonizing PTPs during onset and termination of neointima formation,” FASEB Journal, vol. 21, no. 2, pp. 523–534, 2007.
- P. Levéen, M. Pekny, S. Gebre-Medhin, B. Swolin, E. Larsson, and C. Betsholtz, “Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities,” Genes and Development, vol. 8, no. 16, pp. 1875–1887, 1994.
- G. Liu, X. Li, Y. Li et al., “PPARδ agonist GW501516 inhibits PDGF-stimulated pulmonary arterial smooth muscle cell function related to pathological vascular remodeling,” BioMed Research International, vol. 2013, Article ID 903947, 8 pages, 2013.
- R. N. Martins, J. O. Chleboun, P. Sellers, M. Sleigh, and J. Muir, “The role of PDGF-BB on the development of the collateral circulation after acute arterial occlusion,” Growth Factors, vol. 10, no. 4, pp. 299–306, 1994.
- D. Arora, S. Stopp, S. Böhmer et al., “Protein-tyrosine phosphatase DEP-1 controls receptor tyrosine kinase FLT3 signaling,” The Journal of Biological Chemistry, vol. 286, no. 13, pp. 10918–10929, 2011.
- E. Jandt, K. Denner, M. Kovalenko, A. Östman, and F. D. Böhmer, “The protein-tyrosine phosphatase DEP-1 modulates growth factor-stimulated cell migration and cell-matrix adhesion,” Oncogene, vol. 22, no. 27, pp. 4175–4185, 2003.
- F. Sacco, M. Tinti, A. Palma et al., “Tumor suppressor density-enhanced phosphatase-1 (DEP-1) inhibits the RAS pathway by direct dephosphorylation of ERK1/2 kinases,” The Journal of Biological Chemistry, vol. 284, no. 33, pp. 22048–22058, 2009.
- M. G. Lampugnani, A. Zanetti, M. Corada et al., “Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, β-catenin, and the phosphatase DEP-1/CD148,” Journal of Cell Biology, vol. 161, no. 4, pp. 793–804, 2003.
- C. Chabot, K. Spring, J. P. Gratton, M. Elchebly, and I. Royal, “New role for the protein tyrosine phosphatase DEP-1 in Akt activation and endothelial cell survival,” Molecular and Cellular Biology, vol. 29, no. 1, pp. 241–253, 2009.
- K. Spring, C. Chabot, S. Langlois et al., “Tyrosine phosphorylation of DEP-1/CD148 as a mechanism controlling Src kinase activation, endothelial cell permeability, invasion, and capillary formation,” Blood, vol. 120, no. 13, pp. 2745–2756, 2012.
- A. Duelsner, N. Gatzke, J. Glaser et al., “Granulocyte colony-stimulating factor improves cerebrovascular reserve capacity by enhancing collateral growth in the circle of Willis,” Cerebrovascular Diseases, vol. 33, no. 5, pp. 419–429, 2012.
- I. E. Hoefer, N. van Royen, I. R. Buschmann, J. J. Piek, and W. Schaper, “Time course of arteriogenesis following femoral artery occlusion in the rabbit,” Cardiovascular Research, vol. 49, no. 3, pp. 609–617, 2001.
- F. Trapasso, A. Drusco, S. Costinean et al., “Genetic ablation of Ptprj, a mouse cancer susceptibility gene, results in normal growth and development and does not predispose to spontaneous tumorigenesis,” DNA and Cell Biology, vol. 25, no. 6, pp. 376–382, 2006.
- J. W. Zhu, T. Brdicka, T. R. Katsumoto, J. Lin, and A. Weiss, “Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling,” Immunity, vol. 28, no. 2, pp. 183–196, 2008.
- K. Maeda, R. Hata, and K. A. Hossmann, “Differences in the cerebrovascular anatomy of C57Black/6 and SV129 mice,” NeuroReport, vol. 9, no. 7, pp. 1317–1319, 1998.
- P. Hillmeister, N. Gatzke, A. Dülsner et al., “Arteriogenesis is modulated by bradykinin receptor signaling,” Circulation Research, vol. 109, no. 5, pp. 524–533, 2011.
- H. T. Freyhaus, M. Dagnell, M. Leuchs et al., “Hypoxia enhances platelet-derived growth factor signaling in the pulmonary vasculature by down-regulation of protein tyrosine phosphatases,” The American Journal of Respiratory and Critical Care Medicine, vol. 183, no. 8, pp. 1092–1102, 2011.
- A. Helisch, S. Wagner, N. Khan et al., “Impact of mouse strain differences in innate hindlimb collateral vasculature,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 26, no. 3, pp. 520–526, 2006.
- E. Deindl, I. Buschmann, I. E. Hoefer et al., “Role of ischemia and of hypoxia-inducible genes in arteriogenesis after femoral artery occlusion in the rabbit,” Circulation Research, vol. 89, no. 9, pp. 779–786, 2001.
- H. Busch, I. R. Buschmann, G. Mies, C. Bode, and K. A. Hossmann, “Arteriogenesis in hypoperfused rat brain,” Journal of Cerebral Blood Flow and Metabolism, vol. 23, no. 5, pp. 621–628, 2003.
- I. R. Buschmann, H. Busch, G. Mies, and K. A. Hossmann, “Therapeutic induction of arteriogenesis in hypoperfused rat brain via granulocyte-macrophage colony-stimulating factor,” Circulation, vol. 108, no. 5, pp. 610–615, 2003.
- P. Lindahl, M. Hellström, M. Kalén et al., “Paracrine PDGF-B/PDGF-Rβ signaling controls mesangial cell development in kidney glomeruli,” Development, vol. 125, no. 17, pp. 3313–3322, 1998.
- P. Soriano, “Abnormal kidney development and hematological disorders in PDGF β-receptor mutant mice,” Genes and Development, vol. 8, no. 16, pp. 1888–1896, 1994.
- Y. Chang, B. Ceacareanu, D. Zhuang et al., “Counter-regulatory function of protein tyrosine phosphatase 1B in platelet-derived growth factor- or fibroblast growth factor-induced motility and proliferation of cultured smooth muscle cells and in neointima formation,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 26, no. 3, pp. 501–507, 2006.
- C. J. Desai, N. X. Krueger, H. Saito, and K. Zinn, “Competition and cooperation among receptor tyrosine phosphatases control motoneuron growth cone guidance in Drosophila,” Development, vol. 124, no. 10, pp. 1941–1952, 1997.
- Z. Zhang, I. Nagata, H. Kikuchi et al., “Broad-spectrum and selective serine protease inhibitors prevent expression of platelet-derived growth factor-BB and cerebral vasospasm after subarachnoid hemorrhage: vasospasm caused by cisternal injection of recombinant platelet-derived growth factor-BB,” Stroke, vol. 32, no. 7, pp. 1665–1672, 2001.
- H. Methe, M. Balcells, M. del Carmen Alegret et al., “Vascular bed origin dictates flow pattern regulation of endothelial adhesion molecule expression,” The American Journal of Physiology—Heart and Circulatory Physiology, vol. 292, no. 5, pp. H2167–H2175, 2007.
- L. E. Arias-Romero, S. Saha, O. Villamar-Cruz et al., “Activation of Src by protein tyrosine phosphatase 1B is required for ErbB2 transformation of human breast epithelial cells,” Cancer Research, vol. 69, no. 11, pp. 4582–4588, 2009.
- N. Dube, A. Cheng, and M. L. Tremblay, “The role of protein tyrosine phosphatase 1B in Ras signaling,” Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no. 7, pp. 1834–1839, 2004.
- J. Oshikawa, N. Urao, H. W. Kim et al., “Extracellular SOD-derived H2O2 promotes VEGF signaling in caveolae/lipid rafts and post-ischemic angiogenesis in mice,” PLoS ONE, vol. 5, no. 4, Article ID e10189, 2010.