In Vitro Large Scale Production of Human Mature Red Blood Cells from Hematopoietic Stem Cells by Coculturing with Human Fetal Liver Stromal Cells
Figure 1
Long-term expansion of human erythroid progenitors from cord blood HSCs. (a) The purity of cord blood derived HSCs was analyzed by flow cytometry. The expression of CD8, CD34, CD71, and CD117 was shown. ((b) and (c)) Morphology of the cultured erythroid progenitor cells in different density. (d) Proliferation kinetics were determined by daily measurements in an electronic cell counter. Cumulative cell numbers were calculated as described in Section 2. Results of one optical conditions are shown.
