Effects of Anesthesia and Species on the Uptake or Binding of Radioligands In Vivo in the Göttingen Minipig
Figure 1
Time activity curves (TACs) and Logan plots for yohimbine. (a) Averaged yohimbine TACs for a region of high binding (thalamus) and a region of lower binding (striatum) in pigs (data corrected for amount of injected activity per kg body weight) for comparison of isoflurane and propofol anesthesia. (b) Logan plots of yohimbine thalamus data for 2 representative pigs, one anesthetized with isoflurane (filled circles), and one anesthetized with propofol (open circles). Note the straightness of the fitted line.
