Neuroprotective Effect of Ginseng against Alteration of Calcium Binding Proteins Immunoreactivity in the Mice Hippocampus after Radiofrequency Exposure
Figure 1
Photomicrograph of calbindin D28-k (CB) immunoreactivity (IR) in coronal sections through the hippocampal subfields of sham control (SC) (a, d, g), radiofrequency-exposed (E1.6) (b, e, h), and ginseng-treated (G1.6) (c, f, i) groups. CA1 (a–c) and CA3 areas (g–i) show various CB-positive neurons. In the various layers of CA1, CB IR pyramidal (thin arrows) and other interneuron (thick arrows) cells were noted areas in all three types (a–c). Strong labeling of the granule cells and mossy fibers (MF) was detected in the dentate gyrus which was highly decreased in E1.6 (f). CA3 area of SC revealed few CB immunopositive neurons in the SR of all three types (g–i). SO: stratum oriens; SP: stratum pyramidale; SR: stratum radiatum; SLM: stratum lacunosum moleculare; SL: stratum lucidum; ML: molecular layer; GL: granular layer; PL: polymorphic layer. Scale bar = 100 μm.
