Research Article

Neuroprotective Effect of Ginseng against Alteration of Calcium Binding Proteins Immunoreactivity in the Mice Hippocampus after Radiofrequency Exposure

Figure 2

Magnified image of calbindin D28-k (CB) immunoreactivity (IR) in the subfields of sham control (SC) (a, d, g), radiofrequency-exposed (E1.6) (b, e, h), and ginseng-treated (G1.6) (c, f, i) groups. Loss of staining in the soma (arrows) as well as the dendrites of the neurons in the CA1 area of E1.6 was observed (c). GL of E1.6 (e) displayed weakly labeled granule cells (arrows) as compared with SC (d). Granule cells were highly stained in G1.6 (f). The CA3 area revealed darkly stained neurons with dendrites (arrow) arborizing out, which were noted in SC (g) and G1.6 (i). However, E1.6 (h) displayed very faintly labeled neurons lacking dendritic (arrow) arborizations (i). Scale bar = 50 μm.
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