Research Article

Neuroprotective Effect of Ginseng against Alteration of Calcium Binding Proteins Immunoreactivity in the Mice Hippocampus after Radiofrequency Exposure

Figure 4

Magnified image of parvalbumin (PV) immunoreactivity (IR) in the subfields of sham control (SC) (a, d, g), radiofrequency-exposed (E1.6) (b, e, h), and ginseng-treated (G1.6) (c, f, i) groups. Neurons (arrows) present in the CA1 area of E1.6 (b) showed decrease in PV IR, which appeared to be very highly labeled in SC (a). Similarly, the staining intensity of the neurons in the granular layer was highly decreased in E1.6 (e) along with its axons (arrows) as compared with SC (d) and G1.6 (f). CA3 area also revealed loss of IR in the neurons (arrows) as well as the dendrites of E1.6 (h). Scale bar = 50 μm.
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