Neuroprotective Effect of Ginseng against Alteration of Calcium Binding Proteins Immunoreactivity in the Mice Hippocampus after Radiofrequency Exposure
Figure 6
Magnified image of calretinin (CR) immunoreactivity (IR) in the subfields of sham control (SC) (a, d, g), radiofrequency-exposed (E1.6) (b, e, h), and ginseng-treated (G1.6) (c, f, i) groups. Note the loss of staining in axons (arrows) in the CA1 area of the E1.6 (b) which appear to be intact in SC (a) and G1.6 (c). Decrease in the staining intensity as well as severe loss of infragranular neurons (arrows) was noted in the dentate gyrus of E1.6 (e) as compared with SC (d) and G1.6 (f). CR immunopositive neurons displayed intense dendritic arborization (arrows) in the CA3 area of SC (g) and G1.6 (i), but this was absent in E1.6 (h). Scale bar = 50 μm.
