Sphingosine-1-phosphate-Mediated Mobilization of Hematopoietic Stem/Progenitor Cells during Intravascular Hemolysis Requires Attenuation of SDF-1-CXCR4 Retention Signaling in Bone Marrow

Table 1

Activation of the complement cascade (CC) and increase in free hemoglobin (Hb) level in PB plasma after PHZ, AMD3100, and AMD3100 + PHZ administration.

	Control*	PHZ	AMD3100	PHZ + AMD3100
Activation of CC (increase in C5a level in PB plasma)	1.0	1.5±0.2	1.4±0.3	2.1±0.2
Increase in free Hb level in PB plasma	1.0	1.4±1.0	1.1±0.4	1.3±1.0

∗Values in control mice were assumed to be 1.0.