Anti-Inflammatory Activity and Composition of Senecio salignus Kunth
Table 2
Anti-inflammatory effect of AF on paw edema induced by carrageenan.
Time (H)
% Inhibition
Indomethacin
Senecio salignus
8 mg/kg
50 mg/kg
100 mg/kg
200 mg/kg
400 mg/kg
1
15.1 ± 2.8*
10.3 ± 4.02*
15.03 ± 3.1*
17.5 ± 2.3*
27.5 ± 3.8
2
28.3 ± 3.8*
21.3 ± 2.4*
27.8 ± 3.1*
29.1 ± 3.1*
34.5 ± 2.2*
3
43.4 ± 3.2*
26.6 ± 2.1
47.5 ± 4.02*
44.6 ± 3.8*
57.3 ± 2.6
4
61.1 ± 3.8*
37.2 ± 4.6
58.9 ± 2.8*
63.5 ± 2.2*
70.3 ± 4.5
5
62.2 ± 3.9*
38.9 ± 3.3
60.1 ± 4.7*
62.9 ± 2.04*
80.1 ± 4.5
Results are expressed as percentage of inhibition and mean of eight determinations ± SE. One-way ANOVA, Dunnett test * for comparison of S. salignus with indomethacin-treated groups.
