Review Article

Improving Therapeutic Ratio in Head and Neck Cancer with Adjuvant and Cisplatin-Based Treatments

Table 2

The circadian rhythm of normal oral mucosa cells (data from Bjarnason et al. [37]).

Cycle phaseEarly G1Late G1SG2M

Peak time6 am11 am3 pm4 pm9 pm
Phase markerp27p53cyclin Ecyclin Acyclin B