About this Journal Submit a Manuscript Table of Contents
BioMed Research International
Volume 2013 (2013), Article ID 821498, 4 pages
http://dx.doi.org/10.1155/2013/821498
Research Article

Possible Mechanisms of Fullerene C60 Antioxidant Action

1Research Institute of Biology, Southern Federal University, Rostov-on-Don 344090, Russia
2Research Center for Nanoscale Structure of Matter, Southern Federal University, Rostov-on-Don 344090, Russia
3Department of Physics, Purdue University, West Lafayette, IN 47907, USA

Received 6 June 2013; Revised 2 August 2013; Accepted 13 September 2013

Academic Editor: Claiton Leonetti Lencina

Copyright © 2013 V. A. Chistyakov et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. Back, B. P. Braeckman, and F. Matthijssens, “ROS in aging Caenorhabditis elegans: damage or signaling?” Oxidative Medicine and Cellular Longevity, vol. 2012, Article ID 608478, 14 pages, 2012. View at Publisher · View at Google Scholar
  2. A. Bratic and N. G. Larsson, “The role of mitochondria in aging,” Journal of Clinical Investigation, vol. 123, no. 3, pp. 951–957, 2013.
  3. M. J. Jackson, “Strategies for reducing oxidative damage in ageing skeletal muscle,” Advanced Drug Delivery Reviews, vol. 61, no. 14, pp. 1363–1368, 2009. View at Publisher · View at Google Scholar · View at Scopus
  4. G. Nguyen and A. Torres, “S ystemic antioxidants and skin health,” Journal of Drugs in Dermatology, vol. 11, no. 9, pp. e1–e4, 2012.
  5. D. M. Small, J. S. Coombes, N. Bennett, D. W. Johnson, and G. C. Gobe, “Oxidative stress, anti-oxidant therapies and chronic kidney disease,” Nephrology, vol. 17, no. 4, pp. 311–321, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Martínez, E. Hernández-Marin, and A. Galano, “Xanthones as antioxidants: a theoretical study on the thermodynamics and kinetics of the single electron transfer mechanism,” Food and Function, vol. 3, no. 4, pp. 442–450, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. E. Hernandez-Marin and A. Galano A, “Martinez, C is carotenoids: colorful molecules and free radical quenchers,” Journal of Physical Chemistry B, vol. 117, no. 15, pp. 4050–4061, 2013.
  8. S. Alcaro, S. G. C. hiodo, M. Leopoldini, and F. Ortuso, “Antioxidant efficiency of oxovitisin, a new class of red wine pyranoanthocyanins, revealed through quantum mechanical investigations,” Journal of Chemical Information and Modeling, vol. 53, no. 1, pp. 66–75, 2013.
  9. M. Leopoldini, N. Russo, and M. Toscano, “Gas and liquid phase acidity of natural antioxidants,” Journal of Agricultural and Food Chemistry, vol. 54, no. 8, pp. 3078–3085, 2006. View at Publisher · View at Google Scholar · View at Scopus
  10. J. R. León-Carmona and A. Galano, “Is caffeine a good scavenger of oxygenated free radicals?” Journal of Physical Chemistry B, vol. 115, no. 15, pp. 4538–4546, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. A. Martínez, A. Galano, and R. Vargas, “Free radical scavenger properties of α-mangostin: thermodynamics and kinetics of HAT and RAF mechanisms,” Journal of Physical Chemistry B, vol. 115, no. 43, pp. 12591–12598, 2011. View at Publisher · View at Google Scholar · View at Scopus
  12. A. Galano and A. Martínez, “Capsaicin, a tasty free radical scavenger: mechanism of action and kinetics,” Journal of Physical Chemistry B, vol. 116, no. 3, pp. 1200–1208, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. M. Leopoldini, N. Russo, S. Chiodo, and M. Toscano, “Iron chelation by the powerful antioxidant flavonoid quercetin,” Journal of Agricultural and Food Chemistry, vol. 54, no. 17, pp. 6343–6351, 2006. View at Publisher · View at Google Scholar · View at Scopus
  14. T. Baati, F. Bourasset, N. Gharbi et al., “The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene,” Biomaterials, vol. 33, no. 19, pp. 4936–4946, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. M. K. Manibusan, M. Odin, and D. A. Eastmond, “Postulated carbon tetrachloride mode of action: a review,” Journal of Environmental Science and Health Part C, vol. 25, no. 3, pp. 185–209, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. G. V. Andrievsky, V. I. Bruskov, A. A. Tykhomyrov, and S. V. Gudkov, “Peculiarities of the antioxidant and radioprotective effects of hydrated C60 fullerene nanostuctures in vitro and in vivo,” Free Radical Biology and Medicine, vol. 47, no. 6, pp. 786–793, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. R. Banks, J. R. Speakman, and C. Selman, “Vitamin E supplementation and mammalian lifespan,” Molecular Nutrition and Food Research, vol. 54, no. 5, pp. 719–725, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. M. V. Skulachev, Y. N. Antonenko, V. N. Anisimov et al., “Mitochondrial-targeted plastoquinone derivatives. Effect on senescence and acute age-related pathologies,” Current Drug Targets, vol. 12, no. 6, pp. 800–826, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. Y. Xiao and M. R. Wiesner, “Characterization of surface hydrophobicity of engineered nanoparticles,” Journal of Hazardous Materials, vol. 215-216, pp. 146–151, 2012. View at Publisher · View at Google Scholar · View at Scopus
  20. J. Wong-Ekkabut, S. Baoukina, W. Triampo, I.-M. Tang, D. P. Tieleman, and L. Monticelli, “Computer simulation study of fullerene translocation through lipid membranes,” Nature Nanotechnology, vol. 3, no. 6, pp. 363–368, 2008. View at Publisher · View at Google Scholar · View at Scopus
  21. S. S. Korshunov, V. P. Skulachev, and A. A. Starkov, “High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria,” FEBS Letters, vol. 416, no. 1, pp. 15–18, 1997. View at Publisher · View at Google Scholar · View at Scopus
  22. F. M. Bickelhaupt and E. J. Baerends, “Kohn-Sham density functional theory: predicting and understanding chemistry,” Reviews in Computational Chemistry, vol. 15, pp. 1–86, 2000. View at Scopus
  23. E. R. Johnson and G. A. Dilabio, “Radicals as hydrogen bond donors and acceptors,” Interdisciplinary Sciences, Computational Life Sciences, vol. 1, no. 2, pp. 133–140, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. G. te Velde, F. M. Bickelhaupt, E. J. Baerends, et al., “Chemistry with ADF,” Journal of Computational Chemistry, vol. 22, no. 9, pp. 931–967, 2001. View at Publisher · View at Google Scholar · View at Scopus
  25. S. Grimme, J. Antony, S. Ehrlich, and H. Krieg, “A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu,” Journal of Chemical Physics, vol. 132, no. 15, Article ID 154104, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. C. Lee, W. Yang, and R. G. Parr, “Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density,” Physical Review B, vol. 37, no. 2, pp. 785–789, 1988. View at Publisher · View at Google Scholar · View at Scopus
  27. C. Fonseca Guerra, J.-W. Handgraaf, E. J. Baerends, and F. M. Bickelhaupt, “Voronoi deformation density (VDD) charges: Assessment of the Mulliken, Bader, Hirshfeld, Weinhold, and VDD methods for charge analysis,” Journal of Computational Chemistry, vol. 25, no. 2, pp. 189–210, 2004. View at Publisher · View at Google Scholar · View at Scopus
  28. V. P. Skulachev, “How to clean the dirtiest place in the cell: Cationic antioxidants as intramitochondrial ROS scavengers,” IUBMB Life, vol. 57, no. 4-5, pp. 305–310, 2005. View at Publisher · View at Google Scholar · View at Scopus
  29. F. F. Severin, I. I. Severina, Y. N. Antonenko et al., “Penetrating cation/fatty acid anion pair as a mitochondria-targeted protonophore,” Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 2, pp. 663–668, 2010. View at Publisher · View at Google Scholar · View at Scopus