Analgesic and Anti-Inflammatory Activities of the Methanolic Stem Bark Extract of Nyctanthes arbor-tristis Linn.

Table 2

Tail flick assay: time of measurement of latency of tail flick (sec).

Group	Dose (mg/kg)	Reaction time in (sec)
		0 min	15 min	30 min	60 min	90 min
Control	—	2.74 ± 0.16	2.81 ± 0.12	2.97 ± 0.18	3.01 ± 0.05	2.82 ± 0.12
Standard	5 (i.p)	2.90 ± 0.12 a^@	4.12 ± 0.18 a^@	6.59 ± 0.11 a^@	9.35 ± 0.10 a^@	9.18 ± 0.18 a^@
MENA250	250 (p.o)	2.80 ± 0.12 a^@b^@	2.99 ± 0.20 a^nsb^@	3.67 ± 0.17 a*b^@	5.47 ± 0.20 a^@b^@	5.11 ± 0.06 a^@b^@
MENA500	500 (p.o)	2.85 ± 0.10 a^@b*c^@	3.55 ± 0.12 a*b^nsc^ns	5.29 ± 0.12 a^@b^@c^@	7.75 ± 0.23 a^@b^@c^@	6.92 ± 0.16 a^@b^@c^@

Data are expressed as Mean ± SEM, 𝑛=6 animals in each group. One-way ANOVA was carried out using Turkey’s multiple comparison tests. Comparisons were made between:
a: Control versus Standard, MENA₂₅₀, and MENA₅₀₀.
b: Standard versus MENA₂₅₀ and MENA₅₀₀.
C: MENA₂₅₀ versus MENA₅₀₀.
Symbols represent statistical significance: *𝑃<0.05, ^#𝑃<0.01, ^@𝑃<0.001, ns: nonsignificant.