Analgesic and Anti-Inflammatory Activities of the Methanolic Stem Bark Extract of Nyctanthes arbor-tristis Linn.

Table 3

Tail immersion method: effects of methanolic extract of Nyctanthes arbor-tristis stem barks and morphine on pain induced tail immersion method.

Group	Dose (mg/kg)	Reaction time in (sec)
		0 min	15 min	30 min	60 min	90 min
Control	—	3.02 ± 0.12	2.98 ± 0.17	2.85 ± 0.10	3.08 ± 0.14	3.06 ± 0.11
Standard	5 (i.p)	3.06 ± 0.14 a*	5.23 ± 0.04 a^@	7.58 ± 0.12 a^@	9.72 ± 0.12 a^@	9.15 ± 0.13 a^@
MENA250	250 (p.o)	3.04 ± 0.05 a*b*	3.74 ± 0.13 a^@b^@	4.26 ± 0.11 a^@b^@	5.34 ± 0.18 a^@b^@	5.67 ± 0.20 a^@b^@
MENA500	500 (p.o)	2.98 ± 0.21 a*b*c^ns	3.89 ± 0.05 a^@b^@c*	5.44 ± 0.10 a^@b^@c^@	6.71 ± 0.15 a^@b^@c^@	7.52 ± 0.16 a^@b^@c^@

Data are expressed as Mean ± SEM, 𝑛=6 animals in each group. One-way ANOVA was carried out using Turkey’s multiple comparison tests. Comparisons were made between:
a: Control versus Standard, MENA₂₅₀, and MENA₅₀₀.
b: Standard versus MENA₂₅₀ and MENA₅₀₀.
c: MENA₂₅₀ versus MENA₅₀₀.
Symbols represent statistical significance: *𝑃<0.05, ^#𝑃<0.01, ^@𝑃<0.001, ns: nonsignificant.