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BioMed Research International
Volume 2013 (2013), Article ID 826370, 7 pages
http://dx.doi.org/10.1155/2013/826370
Research Article

Remarkable Anti-Trichomonas vaginalis Activity of Plants Traditionally Used by the Mbyá-Guarani Indigenous Group in Brazil

1Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Avenida Ipiranga 2752, 90610-000 Porto Alegre, RS, Brazil
2Faculdade de Farmácia e Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul, Avenida Ipiranga 2752, 90610-000 Porto Alegre, RS, Brazil

Received 16 April 2013; Accepted 4 June 2013

Academic Editor: Abhay R. Satoskar

Copyright © 2013 Clara Lia Costa Brandelli et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. WHO, Global Incidence and Prevalence of Selected Curable Sexually Transmitted Infections-2008, World Health Organization, Geneva, Switzerland, 2012, http://apps.who.int/iris/bitstream/10665/75181/1/9789241503839_eng.pdf.
  2. D. Petrin, K. Delgaty, R. Bhatt, and G. Garber, “Clinical and microbiological aspects of Trichomonas vaginalis,” Clinical Microbiology Reviews, vol. 11, no. 2, pp. 300–317, 1998. View at Scopus
  3. M. A. Klebanoff, J. C. Carey, J. C. Hauth et al., “Failure of metronidazole to prevent preterm delivery among pregnant women with asymptomatic Trichomonas vaginalis infection,” The New England Journal of Medicine, vol. 345, no. 7, pp. 487–493, 2001. View at Publisher · View at Google Scholar · View at Scopus
  4. F. Grodstein, M. B. Goldman, and D. W. Cramer, “Relation of tubal infertility to history of sexually transmitted diseases,” American Journal of Epidemiology, vol. 137, no. 5, pp. 577–584, 1993. View at Scopus
  5. M. Viikki, E. Pukkala, P. Nieminen, and M. Hakama, “Gynaecological infections as risk determinants of subsequent cervical neoplasia,” Acta Oncologica, vol. 39, no. 1, pp. 71–75, 2000. View at Scopus
  6. T. L. Cherpes, H. C. Wiesenfeld, M. A. Melan et al., “The associations between pelvic inflammatory disease, Trichomonas vaginalis infection, and positive herpes simplex virus type 2 serology,” Sexually Transmitted Diseases, vol. 33, no. 12, pp. 747–752, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. F. Sorvillo, L. Smith, P. Kerndt, and L. Ash, “Trichomonas vaginalis, HIV, and African-Americans,” Emerging Infectious Diseases, vol. 7, no. 6, pp. 927–932, 2001. View at Scopus
  8. B. van der Pol, C. Kwok, B. Pierre-Louis et al., “Trichomonas vaginalis infection and human immunodeficiency virus acquisition in African women,” Journal of Infectious Diseases, vol. 197, no. 4, pp. 548–554, 2008. View at Publisher · View at Google Scholar · View at Scopus
  9. V. Ali and T. Nozaki, “Current therapeutics, their problems, and sulfur-containing-amino-acid metabolism as a novel target against infections by “amitochondriate” protozoan parasites,” Clinical Microbiology Reviews, vol. 20, no. 1, pp. 164–187, 2007. View at Publisher · View at Google Scholar · View at Scopus
  10. J. R. Schwebke and F. J. Barrientes, “Prevalence of Trichomonas vaginalis isolates with resistance to metronidazole and tinidazole,” Antimicrobial Agents and Chemotherapy, vol. 50, no. 12, pp. 4209–4210, 2006. View at Publisher · View at Google Scholar · View at Scopus
  11. R. B. Giordani, P. B. Vieira, M. Weizenmann et al., “Candimine-induced cell death of the amitochondriate parasite Trichomonas vaginalis,” Journal of Natural Products, vol. 73, no. 12, pp. 2019–2023, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. R. B. Giordani, P. B. Vieira, M. Weizenmann et al., “Lycorine induces cell death in the amitochondriate parasite, Trichomonas vaginalis, via an alternative non-apoptotic death pathway,” Phytochemistry, vol. 72, no. 7, pp. 645–650, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. J. L. Ríos and M. C. Recio, “Medicinal plants and antimicrobial activity,” Journal of Ethnopharmacology, vol. 100, no. 1-2, pp. 80–84, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Heinrich, “Ethnobotany and natural products: the search for new molecules, new treatments of old diseases or a better understanding of indigenous cultures?” Current Topics in Medicinal Chemistry, vol. 3, no. 2, pp. 141–154, 2003. View at Scopus
  15. C. L. C. Brandelli, R. B. Giordani, A. J. Macedo, G. A. de Carli, and T. Tasca, “Indigenous traditional medicine: plants for the treatment of diarrhea,” in Nature Helps...: How Plants and Other Organisms Contribute to Solve Health Problems, pp. 1–18, Springer, Berlin, Germany, 1st edition, 2011.
  16. E. Elisabetsky and L. Wannmacher, “The status of ethnopharmacology in Brazil,” Journal of Ethnopharmacology, vol. 38, no. 2-3, pp. 137–143, 1993. View at Scopus
  17. F. L. H. Rego, A. J. Brand, and R. B. Costa, “Genetic resources, biodiversity, traditional knowledge Guarani Kaiowá and local development,” Interações, vol. 11, no. 1, pp. 55–69, 2010.
  18. D. F. Coutinho, L. M. A. Travassos, and F. M. M. Amaral, “Estudo etnobotânico de plantas medicinais utilizadas em comunidades indígenas no estado do Maranhão—Brasil,” Visão Acadêmica, vol. 3, no. 1, pp. 7–12, 2002.
  19. A. H. Gilani and A.-U. Rahman, “Trends in ethnopharmacology,” Journal of Ethnopharmacology, vol. 100, no. 1-2, pp. 43–49, 2005. View at Publisher · View at Google Scholar · View at Scopus
  20. L. S. Diamond, “The establishment of various Trichomonas of animals and man in axenic cultures,” The Journal of Parasitology, vol. 43, no. 4, pp. 488–490, 1957.
  21. M. Duarte, R. B. Giordani, G. A. de Carli, J. A. Zuanazzi, A. J. Macedo, and T. Tasca, “A quantitative resazurin assay to determinate the viability of Trichomonas vaginalis and the cytotoxicity of organic solvents and surfactant agents,” Experimental Parasitology, vol. 123, no. 2, pp. 195–198, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. T. D. Rocha, P. B. Vieira, S. C. B. Gnoatto, T. Tasca, and G. Gosmann, “Anti-Trichomonas vaginalis activity of saponins from Quillaja, Passiflora, and Ilex species,” Parasitology Research, vol. 110, no. 6, pp. 2551–2556, 2012. View at Publisher · View at Google Scholar · View at Scopus
  23. Y. Sun, H. Tong, M. Li, Y. Li, S. Guan, and J. Liu, “Immunological adjuvant effect of Japanese ginseng saponins (JGS) on specific antibody and cellular response to ovalbumin and its haemolytic activities,” Vaccine, vol. 26, no. 47, pp. 5911–5917, 2008. View at Publisher · View at Google Scholar · View at Scopus
  24. M. I. Calvo, “Anti-inflammatory and analgesic activity of the topical preparation of Verbena officinalis L,” Journal of Ethnopharmacology, vol. 107, no. 3, pp. 380–382, 2006. View at Publisher · View at Google Scholar · View at Scopus
  25. S.-W. Lai, M.-S. Yu, W.-H. Yuen, and R. C.-C. Chang, “Novel neuroprotective effects of the aqueous extracts from Verbena officinalis Linn,” Neuropharmacology, vol. 50, no. 6, pp. 641–650, 2006. View at Publisher · View at Google Scholar · View at Scopus
  26. E. Speroni, R. Cervellati, S. Costa et al., “Effects of differential extraction of Verbena officinalis on rat models of inflammation, cicatrization and gastric damage,” Planta Medica, vol. 73, no. 3, pp. 227–235, 2007. View at Publisher · View at Google Scholar · View at Scopus
  27. M. W. Biavatti, C. Farias, F. Curtius et al., “Preliminary studies on Campomanesia xanthocarpa (Berg.) and Cuphea carthagenensis (Jacq.) J.F. Macbr. aqueous extract: weight control and biochemical parameters,” Journal of Ethnopharmacology, vol. 93, no. 2-3, pp. 385–389, 2004. View at Publisher · View at Google Scholar · View at Scopus
  28. B. E. O. Markman, E. M. Bacchi, and E. T. M. Kato, “Antiulcerogenic effects of Campomanesia xanthocarpa,” Journal of Ethnopharmacology, vol. 94, no. 1, pp. 55–57, 2004. View at Publisher · View at Google Scholar · View at Scopus
  29. F. Calzada, L. Yépez-Mulia, and A. Tapia-Contreras, “Effect of Mexican medicinal plant used to treat trichomoniasis on Trichomonas vaginalis trophozoites,” Journal of Ethnopharmacology, vol. 113, no. 2, pp. 248–251, 2007. View at Publisher · View at Google Scholar · View at Scopus
  30. J. Desrivot, J. Waikedre, P. Cabalion et al., “Antiparasitic activity of some New Caledonian medicinal plants,” Journal of Ethnopharmacology, vol. 112, no. 1, pp. 7–12, 2007. View at Publisher · View at Google Scholar · View at Scopus
  31. A. P. Frasson, O. dos Santos, M. Duarte et al., “First report of anti-Trichomonas vaginalis activity of the medicinal plant Polygala decumbens from the Brazilian semi-arid region, Caatinga,” Parasitology Research, vol. 110, no. 6, pp. 2581–2587, 2012. View at Publisher · View at Google Scholar · View at Scopus
  32. P. B. Vieira, R. B. Giordani, G. A. de Carli, J. A. S. Zuanazzi, and T. Tasca, “Screening and bioguided fractionation of Amaryllidaceae species with anti- Trichomonas vaginalis activity,” Planta Medica, vol. 77, no. 10, pp. 1054–1059, 2011. View at Publisher · View at Google Scholar · View at Scopus