Table 2: Amylin derivatives as potential inhibitors of cytotoxicty affected by full-length human amylin.

Amylin derivativePosition of -methylated residueDecrease in cytotoxicityCell line usedReference

Amyli 25%RIN-1056A[37]
Amyli 0%RIN-1056A[37]
Amyli 0%RIN-1056A[110]
Amyli 0%RIN-1056A[110]
Amyli 20 and 2520%RIN 5fm[65]
Amyli 24 and 2650%RIN 5fm[103]
Amyli 50%RIN-1056A[111]
Amyli 50%RIN-1056A[111]
Amyli 45%RIN 5fm[142]
Amyli 3–50%RIN 5fm[142]
Amyli 40%RIN 5fm[142]
Amyli 9, 12, and 130%RIN 5fm[142]
Amyli 20%RIN 5fm[142]
Amyli 15–17 and 190%RIN 5fm[142]
Amyli 40%RIN 5fm[142]
Amyli 23–270%RIN 5fm[142]
Amyli 50%RIN 5fm[142]
Amyli 30 and 32–3450%RIN 5fm[142]