Complex Assessment of the Incidence and Risk Factors of Delirium in a Large Cohort of Cardiac Surgery Patients: A Single-Center 6-Year Experience

Table 3

Significant predictors of delirium in a bivariate analysis-qualitative variables.

Variable	OR	95% CI	“P”
Patient-related conditions
Age > 65 years	2.58	1.94–3.43	<0.0001
Coronary artery disease	1.66	1.09–2.55	0.01
Left anterior descending artery stenosis	1.76	1.14–2.72	0.007
Circumflex artery stenosis	1.56	1.07–2.29	0.01
Right coronary artery stenosis	1.73	1.18–2.54	0.003
Previous myocardial infarction	1.39	1.05–1.85	0.01
Carotid stenosis	1.69	1.23–2.31	0.0006
Peripheral artery disease	1.69	1.21–2.36	0.001
Previous percutaneous coronary intervention	2.52	1.64–3.84	<0.0001
Previous coronary artery bypass grafting	5.39	1.21–20.34	0.003
Mitral valve insufficiency	1.41	1.02–1.94	0.03
Hypertension	0.47	0.36–0.61	<0.001
Chronic obstructive chronic disease	2.06	1.19–3.53	0.005
Liver failure	0.23	0.09–0.53	<0.0001
Ulcerous disease	0.70	0.46–1.05	0.07
Diabetes	1.66	1.25–2.21	<0.0001
Any neurological disorders in anamnesis	1.77	1.28–2.44	<0.0001
Urgent/emergent surgery	2.54	1.92–3.34	<0.0001
EuroSCORE ≥ 6 points	2.32	1.63–3.31	<0.0001
Procedure-related conditions
Postoperative cerebral ischemia	25.01	17.2–31.36	<0.0001
Coronary artery bypass grafting	1.42	0.98–2.07	0.06
On-pump surgery	1.72	1.02–2.93	0.03
Need of inotropic support (postoperatively)	0.43	0.32–0.58	<0.0001
Dopamine use (postoperatively)	0.44	0.33–0.58	<0.0001
Intra-aortic balloon pump (perioperatively)	1.60	1.04–2.44	0.02
Any blood transfusions (perioperatively)	4.65	3.53–6.13	<0.0001
Packed red blood transfusion	5.07	3.85–6.69	<0.0001
Fresh frozen plasma transfusion	2.69	1.96–3.69	<0.0001
Platelet transfusion	4.19	2.72–6.43	<0.0001

CI: confidence interval, OR: odds ratio.