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BioMed Research International
Volume 2013 (2013), Article ID 835859, 12 pages
http://dx.doi.org/10.1155/2013/835859
Research Article

Modeling of the Renal Kinetics of the AT1 Receptor Specific PET Radioligand [11C]KR31173

1Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
2Department of Molecular and Comparative Pathobiology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA

Received 14 April 2013; Accepted 17 July 2013

Academic Editor: Tapas Das

Copyright © 2013 Nedim C. M. Gulaldi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. W. B. Mathews, S.-E. Yoo, S.-H. Lee et al., “A novel radioligand for imaging the AT1 angiotensin receptor with PET,” Nuclear Medicine and Biology, vol. 31, no. 5, pp. 571–574, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Xia, E. Seckin, Y. Xiang et al., “Positron-emission tomography imaging of the angiotensin II subtype 1 receptor in swine renal artery stenosis,” Hypertension, vol. 51, no. 2, pp. 466–473, 2008. View at Publisher · View at Google Scholar · View at Scopus
  3. Z. J. Wang, Z. Szabo, P. Lei, J. Varga, and K. J. R. Liu, “A factor-image framework to quantification of brain receptor dynamic PET studies,” IEEE Transactions on Signal Processing, vol. 53, no. 9, pp. 3473–3487, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. J. J. Frost, K. H. Douglass, H. S. Mayberg et al., “Multicompartmental analysis of [11C]-carfentanil binding to opiate receptors in humans measured by positron emission tomography,” Journal of Cerebral Blood Flow and Metabolism, vol. 9, no. 3, pp. 398–409, 1989. View at Scopus
  5. I. H. Derweesh and A. C. Novick, “Mechanisms of renal ischaemic injury and their clinical impact,” British Journal of Urology, vol. 95, no. 7, pp. 948–950, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Loverre, C. Capobianco, G. Stallone et al., “Ischemia-reperfusion injury-induced abnormal dendritic cell traffic in the transplanted kidney with delayed graft function,” Kidney International, vol. 72, no. 8, pp. 994–1003, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. L. Rosivall, “Intrarenal renin-angiotensin system,” Molecular and Cellular Endocrinology, vol. 302, no. 2, pp. 185–192, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. T. Higuchi, K. Fukushima, J. Xia et al., “Radionuclide imaging of angiotensin II type 1 receptor upregulation after myocardial ischemia-reperfusion injury,” Journal of Nuclear Medicine, vol. 51, no. 12, pp. 1956–1961, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. J. Hilton, F. Yokoi, R. F. Dannals, H. T. Ravert, Z. Szabo, and D. F. Wong, “Column-switching HPLC for the analysis of plasma in PET imaging studies,” Nuclear Medicine and Biology, vol. 27, no. 6, pp. 627–630, 2000. View at Publisher · View at Google Scholar · View at Scopus
  10. D. Marquardt, “An algorithm for least-squares estimation of nonlinear parameters,” Journal of the Society for Industrial and Applied Mathematics, vol. 11, pp. 431–441, 1963.
  11. K. Levenberg, “A method for the solution of certain problems in least squares,” Quarterly of Applied Mathematics, vol. 2, pp. 164–168, 1944.
  12. D. G. Sutton and V. Kempi, “Constrained least-squares restoration and renogram deconvolution: A comparison by simulation,” Physics in Medicine and Biology, vol. 37, no. 1, article 004, pp. 53–67, 1992. View at Publisher · View at Google Scholar · View at Scopus
  13. S. P. Bagby, L. S. Lebard, Z. Luo et al., “ANG II AT1 and AT2 receptors in developing kidney of normal microswine,” American Journal of Physiology, vol. 283, no. 4, pp. F755–F764, 2002. View at Scopus
  14. R. E. Gibson, H. T. Beauchamp, C. Fioravanti, N. Brenner, and H. D. Burns, “Receptor binding radiotracers for the angiotensin II receptor: Radioiodinated [Sar1, Ile8]angiotensin II,” Nuclear Medicine and Biology, vol. 21, no. 4, pp. 593–600, 1994. View at Publisher · View at Google Scholar · View at Scopus
  15. J. De Biasi, “Four open mammillary and catenary compartment models for pharmacokinetics studies,” Journal of Biomedical Engineering, vol. 11, no. 6, pp. 467–470, 1989. View at Scopus
  16. S. P. Bagby, L. S. LeBard, Z. Luo, R. C. Speth, B. E. Ogden, and C. L. Corless, “Angiotensin II type 1 and 2 receptors in conduit arteries of normal developing microswine,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 22, no. 7, pp. 1113–1121, 2002. View at Publisher · View at Google Scholar · View at Scopus
  17. Z. Szabo, R. C. Speth, P. R. Brown et al., “Use of positron emission tomography to study AT1 receptor regulation in vivo,” Journal of the American Society of Nephrology, vol. 12, no. 7, pp. 1350–1358, 2001. View at Scopus
  18. T. G. Zober, W. B. Mathews, E. Seckin et al., “PET imaging of the AT1 receptor with [11C]KR31173,” Nuclear Medicine and Biology, vol. 33, no. 1, pp. 5–13, 2006. View at Publisher · View at Google Scholar · View at Scopus
  19. M. A. Green, C. J. Mathias, L. R. Willis et al., “Assessment of Cu-ETS as a PET radiopharmaceutical for evaluation of regional renal perfusion,” Nuclear Medicine and Biology, vol. 34, no. 3, pp. 247–255, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. Z. Szabo, L. Nyitrai, and C. Sondhaus, “Effects of statistical noise and digital filtering on the parameters calculated from the impulse response function,” European Journal of Nuclear Medicine, vol. 13, no. 3, pp. 148–154, 1987. View at Scopus
  21. S. E. Kim, U. Scheffel, Z. Szabo et al., “In vivo labeling of angiotensin II receptors with a carbon-11-labeled selective nonpeptide antagonist,” Journal of Nuclear Medicine, vol. 37, no. 2, pp. 307–311, 1996. View at Scopus
  22. T. G. Zober, M. E. Fabucci, W. Zheng et al., “Chronic ACE inhibitor treatment increases angiotensin type 1 receptor binding in vivo in the dog kidney,” European Journal of Nuclear Medicine and Molecular Imaging, vol. 35, no. 6, pp. 1109–1116, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. A. J. Allred, M. C. Chappell, C. M. Ferrario, and D. I. Diz, “Differential actions of renal ischemic injury on the intrarenal angiotensin system,” American Journal of Physiology, vol. 279, no. 4, pp. F636–F645, 2000. View at Scopus
  24. J. Kontogiannis and K. D. Burns, “Role of AT1 angiotensin II receptors in renal ischemic injury,” American Journal of Physiology - Renal Physiology, vol. 274, no. 1, pp. F79–F90, 1998. View at Scopus