Microfluidics for Synthesis of Peptide-Based PET Tracers
Figure 3
Microfluidic platform showing reaction setup using an electrochemical concentration chip and a reaction flow cell. 18F-fluorination yields for the four 18F-labeled compounds (protected 18F-FDG: 98%, protected 18F-FMISO: 80%, 18F-flumazenil: 20%, 18F-fluoromethyl bromide: 60%) were comparable to or higher than those obtained by conventional means (reproduced from [3] with permission from Elsevier).
