Alleviation of Hyperglycemia Induced Vascular Endothelial Injury by Exenatide Might Be Related to the Reduction of Nitrooxidative Stress

Figure 4

Treatment with exenatide decreased the plasma nitrotyrosine concentration in DM rats. DM induced a significant increase in the plsma nitrotyrosine concentration, and treatment with exenatide for 45 days significantly decreased the plsma nitrotyrosine concentration. CON, 𝑛=7; DM, 𝐸_min, and 𝐸_max  𝑛=9. **𝑃<0.01 versus CON; ^#𝑃<0.05 versus DM, mean ± SEM.