Research Article

Rotenone Upregulates Alpha-Synuclein and Myocyte Enhancer Factor 2D Independently from Lysosomal Degradation Inhibition

Figure 2

Effect of rotenone on alpha-synuclein (asyn), MEF2D, lamp2A, and hsc70 mRNA levels. Relative quantification (RQ) of asyn, MEF2D, lamp2A, and hsc70 mRNA calculated as ratio to beta-actin in SH-SY5Y treated with 100 and 200 nM rotenone for 24 hours, expressed as fold change versus vehicle (RQ = 1). , repeated measures ANOVA test, followed by Dunnett’s post-test; ; versus vehicle.
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