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BioMed Research International
Volume 2013 (2013), Article ID 849321, 5 pages
Interaction between a Regenerative Matrix and Wound Bed in Nonhealing Ulcers: Results with 16 Cases
1Department of Dermatology, Macchi Foundation Hospital, Viale Borri 57, Varese, Italy
2Zucchi Clinical Institute, Via Zucchi 24, Monza, Italy
3Department of Histopathology, University of Insubria, Via Rossi 9, Varese, Italy
4Department of Experimental and Clinical Biomedical Sciences, University of Insubria, Via Dunant 3, Varese, Italy
Received 29 May 2013; Accepted 26 June 2013
Academic Editor: Davide Vigetti
Copyright © 2013 Alberico Motolese et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- V. Falanga and W. H. Eaglstein, “The “trap” hypothesis of venous ulceration,” The Lancet, vol. 341, no. 8851, pp. 1006–1008, 1993.
- S. Takase, L. Pascarella, L. Lerond, J. J. Bergan, and G. W. Schmid-Schönbein, “Venous hypertension, inflammation and valve remodeling,” European Journal of Vascular and Endovascular Surgery, vol. 28, no. 5, pp. 484–493, 2004.
- M. A. M. Loots, E. N. Lamme, J. Zeegelaar, J. R. Mekkes, J. D. Bos, and E. Middelkoop, “Differences in cellular infiltrate and extracellular matrix of chronic diabetic and venous ulcers versus acute wounds,” Journal of Investigative Dermatology, vol. 111, no. 5, pp. 850–857, 1998.
- H. J. Wallace and M. C. Stacey, “Levels of tumor necrosis factor-α (TNF-α) and soluble TNF receptors in chronic venous leg ulcers—correlations to healing status,” Journal of Investigative Dermatology, vol. 110, no. 3, pp. 292–296, 1998.
- R. W. Tarnuzzer and G. S. Schultz, “Biochemical analysis of acute and chronic wound environments,” Wound Repair and Regeneration, vol. 4, no. 3, pp. 321–325, 1996.
- N. J. Trengove, S. R. Langton, and M. C. Stacey, “Biochemical analysis of wound fluid from nonhealing and healing chronic leg ulcers,” Wound Repair and Regeneration, vol. 4, no. 2, pp. 234–239, 1996.
- M. V. Mendez, A. Stanley, H.-Y. Park, K. Shon, T. Phillips, and J. O. Menzoian, “Fibroblasts cultured from venous ulcers display cellular characteristics of senescence,” Journal of Vascular Surgery, vol. 28, no. 5, pp. 876–883, 1998.
- R. J. Snyder, “Treatment of nonhealing ulcers with allografts,” Clinics in Dermatology, vol. 23, no. 4, pp. 388–395, 2005.
- W. Y. J. Chen and G. Abatangelo, “Functions of hyaluronan in wound repair,” Wound Repair and Regeneration, vol. 7, no. 2, pp. 79–89, 1999.
- K. Harding, Clinical Challenges and Promises of HYAFF Technology in Wound Healing Redefining Hyaluronan, Elsevier BV, 2000.
- R. D. Price, V. Das-Gupta, I. M. Leigh, and H. A. Navsaria, “A comparison of tissue-engineered hyaluronic acid dermal matrices in a human wound model,” Tissue Engineering, vol. 12, no. 10, pp. 2985–2995, 2006.
- G. Gravante, D. Delogu, N. Giordan, G. Morano, A. Montone, and G. Esposito, “The use of hyalomatrix PA in the treatment of deep partial-thickness burns,” Journal of Burn Care and Research, vol. 28, no. 2, pp. 269–274, 2007.
- C. Caravaggi, F. Grigoletto, and N. Scuderi, “Wound bed preparation with a dermal substitute (hyalomatrix PA) facilitates re-epithelialization and healing: results of a multicenter, prospective, observational study on complex chronic ulcers (the FAST study),” Wounds, vol. 23, no. 8, pp. 228–235, 2011.
- C. Dowsett and E. Ayello, “TIME principles of chronic wound bed preparation and treatment,” British Journal of Nursing, vol. 13, no. 15, pp. S16–23, 2004.
- A. Asari, “Novel Functions of Hyaluronan Oligosaccharides,” Science of Hyaluronan Today, February 2005, http://www.glycoforum.gr.jp/science/hyaluronan/hyaluronanE.html.
- A. Passi, P. Sadeghi, H. Kawamura et al., “Hyaluronan suppresses epidermal differentiation in organotypic cultures of rat keratinocytes,” Experimental Cell Research, vol. 296, no. 2, pp. 123–134, 2004.
- D. Jiang, J. Liang, and P. W. Noble, “Hyaluronan as an immune regulator in human diseases,” Physiological Reviews, vol. 91, no. 1, pp. 221–264, 2011.
- G. Galassi, P. Brun, M. Radice et al., “In vitro reconstructed dermis implanted in human wounds: degradation studies of the HA-based supporting scaffold,” Biomaterials, vol. 21, no. 21, pp. 2183–2191, 2000.