Research Article

Structural and Sequence Similarities of Hydra Xeroderma Pigmentosum A Protein to Human Homolog Suggest Early Evolution and Conservation

Figure 2

Conserved domains in hydra XPA. (a) Prediction of domains in hydra XPA by SMART: two Pfam domains XPA-N (amino acid 83 to 115) and XPA-C (amino acid 115 to 167) are present in the 257 amino acid long sequence. (b) Comparison of hydra XPA-N and -C domains with counterparts from other animals by multiple sequence alignment using ClustalW. Sequence of the XPA-C Pfam domain (box) is highly conserved across species. (Accession numbers of all sequences are given in Section 2).
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