Table 3: values retrieved by statistical analyses of single-cell gene expressions in analyzed groups of cells.

Statistical testCompared cells value

Genes of pluripotency

Two-tailed Mann-Whitney test OLCs versus oocytesLIN28 (P = 0.00078),
STELLA (P = 1.0766 × 10−6),
NANOG (P = 8.5203 × 10−6),
SOX-2 (P = 2.2075 × 10−7),
UTF1 (P = 1.1288 × 10−5),
CDH1 (P = 1.0766 × 10−6),
CRKRS (P = 2.2075 × 10−7)

Two-tailed Mann-Whitney testOLCs versus hESCsCD9 (P = 0.00036),
NANOS (P = 0.00097),
STELLA (P = 0.00154),
STAT3 (P = 0.00154),
UTF1 (P = 0.00154),
LIN28 (P = 0.00242)

Two-tailed Mann-Whitney test OLCs versus fibroblastsNANOS (P = 0.00036),
LIN28 (P = 0.00036),
STELLA (P = 0.00036),
CD9 (P = 0.00036),
SOX-2 (P = 0.00036),
OCT4A (P = 0.00036),
MEST (P = 0.00060),
STAT3 (P = 0.00242)

One-Way ANOVAAll types of cells KIT (P ≤ 1 × 10−8),
STELLA (P ≤ 1 × 10−8),
OCT4A (P = 6.86 × 10−6),
LIN28 (P ≤ 1 × 10−8),
NANOG (P = 1.3 × 10−7),
SOX-2 (P ≤ 1 × 10−8),
UTF1 (P = 1 × 10−8),
TDGF1 (P = 0.00167408),
LIN28B (P ≤ 1 × 10−8),
TERT (P ≤ 1 × 10−8),
CD9 (P ≤ 1 × 10−8),
NANOS (P ≤ 1 × 10−8),
CDH1 (P ≤ 1 × 10−8),
STAT3 (P = 4.67 × 10−6),
MEST (P = 5.7 × 10−7),
CRKRS (P ≤ 1 × 10−8).

Oocyte-specific genes

Two-tailed Mann-Whitney testOLCs versus oocytesBNC1 (P = 0.00011)

Genes of meiosis

Two-tailed Mann-Whitney testOLCs versus oocytesMSH5 (P = 0.00204),
REC8 (P = 0.00166)

Legend: OLCs: oocyte-like cells; hESCs: human embryonic stem cells.