Comparative Proteomic Analysis of Peritoneal Dialysate from Chronic Glomerulonephritis Patients

Table 2

Gene ontology analysis of 8 differentially expressed proteins.

Spot number^a	Protein name	Subcellular location	Biological process	Molecular function
P01	Ig mu chain C region	Plasma membrane	Immune response	Antigen binding
P02	Fibrinogen gamma chain	Extracellular space	Platelet activation, platelet degranulation, protein polymerization, response to calcium ion, and signal transduction	Cell surface binding and metal ion binding
P03/P04	C-reactive protein	Extracellular space	Acute-phase response, complement activation, regulation of lipid storage, regulation of macrophage, opsonization, protein polymerization, response to hypoxia, and response to lead ion	Cell surface binding, cholesterol binding, choline binding, low-density lipoprotein particle binding, and metal ion binding
P05	Ig delta chain C region	Extracellular space	Immune response	Antigen binding
P06	Alpha-1-antitrypsin	Extracellular space	Acute-phase response, platelet activation, platelet degranulation, and regulation of proteolysis	Serine-type endopeptidase inhibitor activity
P07/P08	Histidine-rich glycoprotein	Extracellular space	Angiogenesis, chemotaxis, regulation of angiogenesis, regulation of cell adhesion, regulation of cell growth and proliferation, regulation of fibrinolysis, platelet activation and degranulation, regulation of immune, response to tumor cell, and regulation of gene expression	Cell surface binding, cysteine-type endopeptidase inhibitor activity, heme binding, heparan sulfate proteoglycan binding, heparin binding, immunoglobulin binding, metal ion binding, serine-type endopeptidase inhibitor activity, and zinc ion binding
P09	Apolipoprotein A-I	Extracellular space	Cholesterol metabolism, lipid metabolism, lipid transport, steroid metabolism, sterol metabolism, and transport	Cell surface binding, heme binding, heparin binding, immunoglobulin binding, metal ion binding, and zinc ion binding
P10	Serum amyloid P-component	Extracellular space	Acute-phase response and protein folding	Metal ion binding and unfolded protein binding