Hyperpolarization-Activated Current, , in Mathematical Models of Rabbit Sinoatrial Node Pacemaker Cells
Figure 6
Numerical reconstruction of the time course of during pacemaker activity of rabbit sinoatrial node cells. (a) Experimentally recorded action potentials of a single rabbit SA nodal pacemaker cell. (b) Associated time derivative (). (c) Associated time course of as reconstructed using the membrane potential values of the recorded action potentials and mathematical models of this current in rabbit sinoatrial node pacemaker cells. Also shown is the net membrane current (), as derived from , where and denote membrane capacitance and membrane potential, respectively.
