Assessment of Respiration-Induced Motion and Its Impact on Treatment Outcome for Lung Cancer

Table 2

Relationship of GTV centroid 3D vector with clinical and anatomic factors by logistic regression.

Clinical and anatomic factors	𝑃 value
Gender	0.198
Age	0.095
Histology	0.114
fLR	0.073
fAP	0.111
fSI	0.001
GTV volume (cm^3)	0.046
Attachment degree to rigid structure	0.008

Logistic regression suggested that the tumor centriod 3D vector was associated with GTV volume, fSI (the superior-inferior tumor location in the lung) and the attachment degree to rigid structure (e.g., chest wall, vertebrae, or mediastinum).
NSCLC: nonsmall cell lung cancer; SCLC: small cell lung cancer; fLR, fAP, fSI: fractional left-right, anterior-posterior, and superior-inferior location, respectively; GTV: gross tumor volume; attachment degree to rigid structure: the ratio of the longest diameter attached to the rigid structure divided by longest diameter of the tumor in transversal plane.