Table 2: Relationship of GTV centroid 3D vector with clinical and anatomic factors by logistic regression.

Clinical and anatomic factors value

Gender0.198
Age0.095
Histology0.114
fLR0.073
fAP0.111
fSI0.001
GTV volume (cm3)0.046
Attachment degree to rigid structure0.008

Logistic regression suggested that the tumor centriod 3D vector was associated with GTV volume, fSI (the superior-inferior tumor location in the lung) and the attachment degree to rigid structure (e.g., chest wall, vertebrae, or mediastinum).
NSCLC: nonsmall cell lung cancer; SCLC: small cell lung cancer; fLR, fAP, fSI: fractional left-right, anterior-posterior, and superior-inferior location, respectively; GTV: gross tumor volume; attachment degree to rigid structure: the ratio of the longest diameter attached to the rigid structure divided by longest diameter of the tumor in transversal plane.