Evaluation of a Thiolated Chitosan Scaffold for Local Delivery of BMP-2 for Osteogenic Differentiation and Ectopic Bone Formation

Figure 2

Evaluation of the interaction between BMP-2 and Thio-CS. The interaction was evaluated by SDS-PAGE (a) and Western blotting (b). (c) In vitro cumulative release of BMP-2 from the Thio-CS and the Col-gel. The arrow indicates BMP-2 which detected by the BMP-2 antibody. M is a molecular weight marker. Black dotted line is the border line between the stacking and the separating gel. The indicated values are means ± SD (𝑛=3), ^∗𝑃<0.05, ^∗∗𝑃<0.005 as compared with those of the Col-gel at the same time point.

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(b)

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