Table 5: Genes which were significantly up-regulated in human oocytes at different stages of maturity.

Up-regulated genes at different stages of oocyte maturity
GV
(immature)
MI
(immature)
MII
(mature)
References

RBBP8, ATR BRAP, BUB1B, BUB3 RBBP7, RBL2 Gasca et al., 2007 [2]
GBX1, HOXA7 HOXA1, HEX Huntriss et al., 2006 [19]

Molecular functions of differently expressed genes
(GV versus MII oocytes)
GV
Up-regulated genes
(number)
GV
Down-regulated genes
(number)
References

(i) Nucleic acid binding (149)(i) Nucleic acid binding (235)
(ii) Zinc finger transcription factor (58)(ii) Ribosomal protein (101)
(iii) KRAB box transcription factor (41)(iii) Receptor (39)
(iv) Ligase (31)(iv) Translation factor (22)
(v) Chaperone (25)(v) Ribonucleoprotein (15)Wells and Patrizio, 2008 [26]
(vi) Synthase and synthetase (25)(vi) Translation elongation factor (14)
(vii) Receptor (22)(vii) Signaling molecule (13)
(viii) Other RNA-binding factors (19)(viii) G-protein coupled receptor
(ix) mRNA processing factor (17)(ix) Tubulin