Clinical Study

Infliximab Extends the Duration until the First Surgery in Patients with Crohn’s Disease

Table 3

Factors associated with the nonoperative rate until the first surgery (univariate analysis).

Number of patients 50% nonoperation time (months)P value

Sex
 Male71 84<0.05
 Female33142
Type of disease
 Ileitis/ileocolitis 9598<0.05
 Colitis 9Undefined
The age of onset
 Less than 2039117N.S.
 20 or more6598
The date of onset
 Before 200174107N.S
 After 200230Undefined
Corticosteroid
 (+)33 126<0.05
 (−)71 91
Immunomodulator
 (+)37 169<0.05
 (−)6784
Infliximab
 (+)39256<0.05
 (−)6578

Undefined: nonoperation time is greater than 50% at the last time point. N.S.: not significant.