Clinical Study
Infliximab Extends the Duration until the First Surgery in Patients with Crohn’s Disease
Table 3
Factors associated with the nonoperative rate until the first surgery (univariate analysis).
| | Number of patients | 50% nonoperation time (months) | P value |
| Sex | | | | Male | 71 | 84 | <0.05 | Female | 33 | 142 | | Type of disease | | | | Ileitis/ileocolitis | 95 | 98 | <0.05 | Colitis | 9 | Undefined | | The age of onset | | | | Less than 20 | 39 | 117 | N.S. | 20 or more | 65 | 98 | | The date of onset | | | | Before 2001 | 74 | 107 | N.S | After 2002 | 30 | Undefined | | Corticosteroid | | | | (+) | 33 | 126 | <0.05 | (−) | 71 | 91 | | Immunomodulator | | | | (+) | 37 | 169 | <0.05 | (−) | 67 | 84 | | Infliximab | | | | (+) | 39 | 256 | <0.05 | (−) | 65 | 78 | |
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Undefined: nonoperation time is greater than 50% at the last time point. N.S.: not significant.
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