Table 1: Demographic, clinical features, and BDNF serum levels in different study groups.

DiagnosisCTRLADFTDLBDVADPD

Sample size16926628409130
Demographic variables
 Gender (% F)49%67%54%68%67%30%
 differences versus CTRL =<0.0010.6880.0520.0060.073
 Age48.0 ± 15.780.1 ± 7.171.7 ± 9.979.2 ± 5.681.9 ± 7.567.6 ± 8.4
 differences versus CTRL =<0.001<0.001<0.001<0.001<0.001
Clinical variables
 MMSE score>2713.6 ± 8.016.1 ± 6.615.9 ± 7.414.8 ± 8.025.4 ± 2.0
 HY score3.58 ± 0.5
Pharmacological treatment
 Neuroleptics (−/+)*118/14814/1414/2644/4726/44
 Benzodiazepines (−/+)167/9917/1128/1258/3330/0
 Antidepressants (−/+)142/12412/1620/2027/6417/13
 Mood stabilizers antiepileptics (−/+)237/2920/837/374/1730/0
 Cholinesterase inhibitors (−/+)193/7327/121/1987/430/0
 L-DOPA (−/+)266/028/040/091/00/30
Serum BDNF
 ng/mL (mean ± SD)39.89 ± 9.4833.16 ± 12.431.19 ± 9.6831.71 ± 11.633.06 ± 12.446.13 ± 15.3

(−/+): not treated/treated.