Effect of Experimental Infection with Haemonchus contortus on Parasitological and Local Cellular Responses in Resistant and Susceptible Young Creole Goats

Table 3

(a) Histopathological semi-quantitative analysis of eosinophils and mononuclear cells density within the abomal mucosa of resistant and susceptible Creole kids at 49 days post-infection for challenge 1 and 42 days-post-infection for challenge 2. (b) Globules leukocytes counts within the abomasal mucosa of resistant and susceptible Creole kids at 49 days post-infection for challenge 1 and 42 days-post-infection for challenge 2. Values correspond to the mean cell counts ± standard deviations.

(a)  

	Challenge 1		Challenge 2
	^1Eosi	^2Mono	Eosi	Mono
^3Resistant	2	3	2	2
^4Susceptible	3	2	2	2
^5Control	0	1	0	1

1Eosi: intensity of eosinophil infiltration in abomasal mucosa: (1) 1–8 cells/mm²; (2) 9–20 cells/mm²; (3) more than 20 cells/mm².
²Mono: intensity of mononuclear cell infiltration in abomasal mucosa: (1) 1–8 cells/mm²; (2) 9–20 cells/mm²; (3) more than 20 cells/mm².
³Resistant: resistant kids (𝑛=4 for challenge 1 and 𝑛=6 for challenge 2) infected with 10,000 H. contortus infective larvae (L3) at day 0 postinfection.
⁴Susceptible: susceptible kids (𝑛=4 for challenge 1 and 𝑛=6 for challenge 2) infected with 10,000 H. contortus infective larvae (L3) at day 0 postinfection.
⁵Control: noninfected kids (𝑛=2 for both challenges half resistant and half susceptible).

(b)  

	^1Challenge 1	^1Challenge 2
^2Resistant	6.3 (1.6)	2.2 (0.2)
^3Susceptible	2.7 (0.6)	0.9 (1.5)
^4Control	0	0
𝑃 value	0.04	0.14

1Challenges 1 and 2: first and second challenges with 10,000 H. contortus L3.
²Resistant: resistant kids (𝑛=4 for challenge 1 and 𝑛=6 for challenge 2) infected with 10,000 H. contortus infective larvae (L3) at day 0 postinfection.
³Susceptible: susceptible kids (𝑛=4 for challenge 1 and 𝑛=6 for challenge 2) infected with 10,000 H. contortus infective larvae (L3) at day 0 postinfection.
⁴Control: noninfected kids (𝑛=2 for both challenges half resistant and half susceptible).