Table 6: Logistic regression of anomalous cell (mean ± SD/1000 cells) for HNC risk.

Anomalous cell
(mean)
Controls/patientsCrude OR (95% CI) Adjusted ORb (95% CI) Adjusted ORc (95% CI)

MNa
 Low (≤3.00)44/121.00 (reference)1.00 (reference)1.00 (reference)
 High (>3.00)13/338.63 (3.24–22.98)<0.000118.13 (5.00–65.62)<0.000169.06 (5.50–185.12)0.001
BNa
 Low (≤4.10)45/171.00 (reference)1.00 (reference)1.00 (reference)
 High (>4.10)12/285.62 (2.07–15.24)0.0014.91 (1.60–14.66)0.0041.87 (0.31–11.11)NS

OR: odds ratio, CI: confidence interval.
aThe 75th percentiles of the controls’ MN and BN frequencies were used as the cutoffs to assign the study subjects to either the low-frequency group or the high-frequency group.
bAdjusted for age and gender.
cAdjusted for age, gender, tobacco (smoking and chewing), alcohol, and occupational exposure.