Oxidative Stress and Antimicrobial Activity of Chromium(III) and Ruthenium(II) Complexes on Staphylococcus aureus and Escherichia coli

Table 2

Minimum inhibitory concentrations (MICs) in µg/mL and fractional inhibitory concentration indices (FICIs) of [Cr(phen)₃]³⁺ in combination with ciprofloxacin against Staphylococcus aureus ATCC 29213*.

	Ciprofloxacin (MIC = 0.5)
[Cr(phen)3]^3+ (MIC = 1)		MICA−C	FIC
MICC−A	FIC	0.033	0.066
0.5	0.5	FICIC+A=0.566
0.25	0.25	FICIC+A=0.316
0.125	0.125	FICIC+A=0.191

∗ MIC_C−A: MIC of [Cr(phen)₃]³⁺ in combination with ciprofloxacin. MIC_A−C: MIC of ciprofloxacin in combination with [Cr(phen)₃]³⁺. FIC: fractional inhibitory concentration. FICI_C+A: fractional inhibitory concentration index (FIC of [Cr(phen)₃]³⁺ plus FIC of ciprofloxacin).