Oxidative Stress and Antimicrobial Activity of Chromium(III) and Ruthenium(II) Complexes on Staphylococcus aureus and Escherichia coli

Table 3

Minimum inhibitory concentrations (MICs) in µg/mL and fractional inhibitory concentration indices (FICIs) of [Cr(phen)₃]³⁺ in combination with ciprofloxacin against Escherichia coli ATCC 25922*.

	Ciprofloxacin (MIC = 0.25)
[Cr(phen)3]^3+ (MIC = 0.125)		MICA−C	FIC
MICC−A	FIC	0.016	0.064
0.064	0.512	FICIC+A=0.576
0.032	0.256	FICIC+A=0.320
0.016	0.128	FICIC+A=0.192
0.008	0.064	FICIC+A=0.128
0.004	0.032	FICIC+A=0.096

∗ MIC_C−A: MIC of [Cr(phen)₃]³⁺ in combination with ciprofloxacin. MIC_A−C: MIC of ciprofloxacin in combination with [Cr(phen)₃]³⁺. FIC: fractional inhibitory concentration. FICI_C+A: fractional inhibitory concentration index (FIC of [Cr(phen)₃]³⁺ plus FIC of ciprofloxacin).