Research Article

A Comparison between Use of Spray and Freeze Drying Techniques for Preparation of Solid Self-Microemulsifying Formulation of Valsartan and In Vitro and In Vivo Evaluation

Table 2

Evaluation parameters of liquid SMEF bathes.

BatchEmulsification efficiencyFreeze thawingGlobule size
(nm)
(mean ± SD)
Polydispersity index
(mean ± SD)
Zeta potential
(mV)
(mean ± SD)

F1DUnstable
F2CUnstable
F3CUnstable
F4BStable
F5AStable
F6CUnstable
F7CUnstable
F8BStable
F9AStable
F10AUnstable
F11DUnstable
F12DUnstable
F13CUnstable
F14BStable
F15AStable